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Articles Published Processes
8/7/2026 9:40:27 AM | Browse: 1 | Download: 0
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Received |
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2025-11-14 10:03 |
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Peer-Review Started |
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2025-11-17 00:37 |
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First Decision by Editorial Office Director |
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2025-12-02 07:36 |
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Return for Revision |
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2025-12-02 07:36 |
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Revised |
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2025-12-03 00:23 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-05 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-06 00:47 |
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Articles in Press |
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2026-01-06 00:47 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-08 07:09 |
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Publish the Manuscript Online |
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2026-08-07 09:40 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Correspondence |
| Article Title |
Letter to the Editor: Surgical safety of RAPIDO-style total neoadjuvant therapy: Reassuring early outcomes with important nuances.
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Renata D’Alpino Peixoto |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Renata D’Alpino Peixoto, FAHA, MD, PhD, Department of Medical Oncology, British Columbia Cancer, 600 West 10th Avenue, Vancouver V5Z4E6, British Columbia, Canada. renata.peixoto@bccancer.bc.ca |
| Key Words |
Total neoadjuvant therapy; Rectal cancer; RAPIDO protocol; Surgical outcomes; Chemoradiotherapy |
| Core Tip |
This letter highlights real-world data showing that Rectal Cancer and Preoperative Induction Therapy Followed by Dedicated Operation (RAPIDO)-style total neoadjuvant therapy does not appear to increase surgical difficulty or early postoperative morbidity compared with standard long-course chemoradiotherapy. Despite prolonged intervals before surgery, key oncologic and technical metrics - such as R0 resection, total mesorectal excision completeness, and complication rates - were maintained, while stoma-related outcomes may even improve. These findings offer reassurance as total neoadjuvant therapy becomes increasingly integrated into management of locally advanced rectal cancer and underscore the need for future prospective studies incorporating objective measures of operative complexity. |
| Publish Date |
2026-08-07 09:40 |
| Citation |
Peixoto RD. Letter to the Editor: Surgical safety of RAPIDO-style total neoadjuvant therapy: Reassuring early outcomes with important nuances.. World J Gastrointest Oncol 2026; 18(8): 116571
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| URL |
https://www.wjgnet.com/1948-5204/full/v18/i8/116571.htm |
| DOI |
https://doi.org/10.4251/wjgo.116571 |
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