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Articles Published Processes
5/26/2026 5:34:19 AM | Browse: 1 | Download: 15
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Received |
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2025-11-18 04:22 |
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Peer-Review Started |
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2025-11-18 04:22 |
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First Decision by Editorial Office Director |
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2026-01-14 08:34 |
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Return for Revision |
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2026-01-14 08:34 |
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Revised |
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2026-01-27 08:30 |
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Publication Fee Transferred |
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2026-02-03 23:06 |
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Second Decision by Editor |
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2026-03-05 02:53 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-05 09:59 |
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Articles in Press |
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2026-03-05 09:59 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-12 03:39 |
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Publish the Manuscript Online |
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2026-05-26 05:34 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
First large-scale prospective evaluation of serum S100A6 as a complementary biomarker for early pancreatic cancer detection
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Go Eun Bae, Sang-Mi Kim, Jong Kyun Lee and Soo-Youn Lee |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Research Foundation of Korea Grant |
2021R1A2C1006409 |
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| Corresponding Author |
Soo-Youn Lee, Director, MD, PhD, Professor, Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, South Korea. suddenbz@skku.edu |
| Key Words |
S100A6; Early pancreatic cancer; Serum biomarker; Carbohydrate antigen 19-9; Carcinoembryonic antigen |
| Core Tip |
This large-scale case-control study is the first to evaluate the clinical potential of serum S100A6 as a biomarker for pancreatic cancer (PC). When used together with carbohydrate antigen 19-9 (CA19-9), serum S100A6 significantly improved diagnostic accuracy over CA19-9 alone. Importantly, the triple panel including S100A6, CA19-9, and carcinoembryonic antigen significantly improved the differentiation of early-stage PC from chronic pancreatitis. These findings suggest that serum S100A6 may contribute to earlier and more accurate diagnosis of PC. Such improvement could enable timely identification of patients eligible for curative resection. Additional validation in independent and diverse patient populations is warranted. |
| Publish Date |
2026-05-26 05:34 |
| Citation |
Bae GE, Kim SM, Lee JK, Lee SY. First large-scale prospective evaluation of serum S100A6 as a complementary biomarker for early pancreatic cancer detection. World J Gastroenterol 2026; 32(21): 116581 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i21/116581.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i21.116581 |
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