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Articles Published Processes
7/14/2026 5:50:24 AM | Browse: 1 | Download: 0
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Received |
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2025-11-20 05:44 |
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Peer-Review Started |
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2025-11-20 05:45 |
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First Decision by Editorial Office Director |
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2026-01-20 08:19 |
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Return for Revision |
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2026-01-20 08:19 |
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Revised |
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2026-03-10 00:59 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-04-09 02:32 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-09 08:37 |
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Articles in Press |
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2026-04-09 08:37 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-07 07:27 |
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Publish the Manuscript Online |
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2026-07-14 05:50 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Correspondence |
| Article Title |
Letter to the Editor: Intradiscal platelet-rich plasma for discogenic low back pain - promise or premature adoption?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Alex Guedes, Enilton de Santana Ribeiro de Mattos, Eduardo Silva Reis Barreto and César Romero Antunes Júnior |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Alex Guedes, Associate Professor, MD, PhD, Departamento de Cirurgia Experimental e Especialidades Cirúrgicas, Faculdade de Medicina da Bahia, Universidade Federal da Bahia, Praça XV de novembro S/N.º, Largo do Terreiro de Jesus, Salvador 40026-010, Bahia, Brazil. alexguedes2003@yahoo.com.br |
| Key Words |
Platelet-rich plasma; Discogenic low back pain; Intradiscal injection; Regenerative orthopedics; Quality of life |
| Core Tip |
Current treatment options for discogenic low back pain remain limited in their ability to provide durable symptom relief and structural restoration. In this editorial, we discuss platelet-rich plasma (PRP) as a potential biological treatment. The growth factor content of PRP may help counteract disc catabolism, although it remains uncertain whether these mechanisms translate into meaningful clinical regeneration. Two randomized trials reported modest or no clear between-group benefit, whereas uncontrolled studies have suggested symptomatic improvement. A recent quasi-experimental study found early improvements in pain and function without major adverse events, although important confounding factors remained. Overall, the current evidence supports continued clinical equipoise, emphasis on patient-centered outcomes, and adequately powered, blinded trials before broader clinical adoption of intradiscal PRP. |
| Publish Date |
2026-07-14 05:50 |
| Citation |
Guedes A, de Mattos ESR, Barreto ESR, Antunes Júnior CR. Letter to the Editor: Intradiscal platelet-rich plasma for discogenic low back pain - promise or premature adoption? World J Orthop 2026; 17(7): 116587
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| URL |
https://www.wjgnet.com/2218-5836/full/v17/i7/116587.htm |
| DOI |
https://doi.org/10.5312/wjo.116587 |
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