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3/27/2026 12:17:01 PM | Browse: 1 | Download: 0
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 116619
Country China
Received
2025-11-17 03:15
Peer-Review Started
2025-11-17 03:15
First Decision by Editorial Office Director
2025-11-24 12:00
Return for Revision
2025-11-24 12:00
Revised
2025-12-04 16:31
Publication Fee Transferred
Second Decision by Editor
2025-12-31 02:31
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-31 06:52
Articles in Press
2025-12-31 06:52
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-27 07:16
Publish the Manuscript Online
2026-03-27 12:17
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Anesthesiology
Manuscript Type Correspondence
Article Title Letter to the Editor: Toward immune-adaptive anesthesia: Rethinking dexmedetomidine beyond sedation in gastrointestinal cancer surgery
Manuscript Source Invited Manuscript
All Author List Chu-Chu Hu, Ning Li, Bo-Yi Wang, Yong-Wei Yu and Wei Yu
ORCID
Author(s) ORCID Number
Yong-Wei Yu http://orcid.org/0000-0001-8319-7707
Funding Agency and Grant Number
Corresponding Author Yong-Wei Yu, Department of Intensive Care Unit, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Shangcheng District, Hangzhou 310003, Zhejiang Province, China. yuyongwei@zju.edu.cn
Key Words Dexmedetomidine; Immune-adaptive anesthesia; Perioperative care; Gastrointestinal cancer surgery; Postoperative recovery
Core Tip Anesthetic agents influence postoperative recovery far beyond sedation. This letter introduces the concept of immune-adaptive anesthesia, highlighting dexmedetomidine’s capacity to modulate perioperative immune balance and accelerate recovery after gastrointestinal cancer surgery. By integrating anesthetic immunomodulation with surgical precision and evidence-based nursing interventions-such as thermoregulation, stress control, and early mobilization-the perioperative team can collectively enhance immune resilience, reduce complications, and achieve more holistic, patient-centered recovery outcomes in oncologic surgery.
Publish Date 2026-03-27 12:17
Citation

Hu CC, Li N, Wang BY, Yu YW, Yu W. Letter to the Editor: Toward immune-adaptive anesthesia: Rethinking dexmedetomidine beyond sedation in gastrointestinal cancer surgery. World J Gastrointest Surg 2026; 18(3): 116619

URL https://www.wjgnet.com/1948-9366/full/v18/i3/116619.htm
DOI https://dx.doi.org/10.4240/wjgs.v18.i3.116619
Full Article (PDF) WJGS-18-116619-with-cover.pdf
Manuscript File 116619_Auto_Edited_021601.docx
Answering Reviewers 116619-answering-reviewers.pdf
Audio Core Tip 116619-audio.mp3
Conflict-of-Interest Disclosure Form 116619-conflict-of-interest-statement.pdf
Copyright License Agreement 116619-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 116619-non-native-speakers.pdf
Peer-review Report 116619-peer-reviews.pdf
Scientific Misconduct Check 116619-scientific-misconduct-check.png
Scientific Editor Work List 116619-scientific-editor-work-list.pdf
CrossCheck Report 116619-crosscheck-report.pdf