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Articles Published Processes
4/21/2026 8:57:44 AM | Browse: 21 | Download: 109
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Received |
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2025-11-19 07:42 |
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Peer-Review Started |
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2025-11-19 07:42 |
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First Decision by Editorial Office Director |
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2025-12-24 10:13 |
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Return for Revision |
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2025-12-24 10:13 |
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Revised |
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2026-01-07 18:29 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-03 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-03 05:50 |
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Articles in Press |
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2026-02-03 05:50 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-10 08:17 |
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Publish the Manuscript Online |
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2026-04-21 08:57 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Treatment of chronic hepatitis B infection in infants and young children: A systematic review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Simona Carrera, Chiara Rubino, Elisa Bartolini and Giuseppe Indolfi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Simona Carrera, MD, Pediatric and Liver Unit, Meyer Children's Hospital IRCCS, Viale Gaetano Pieraccini 24, Florence 50139, Tuscany, Italy. simona.carrera@meyer.it |
| Key Words |
Chronic hepatitis B virus infection; Children; Functional cure; Hepatitis B surface antigen loss; Antiviral treatment |
| Core Tip |
Chronic hepatitis B is a major global health issue, largely driven by mother-to-child transmission. Spontaneous hepatitis B surface antigen seroclearance occurs at about 1% per year. Emerging evidence suggests that starting antiviral therapy at a young age might lead to higher functional cure rates. This review examines evidence and implications of early treatment. |
| Publish Date |
2026-04-21 08:57 |
| Citation |
Carrera S, Rubino C, Bartolini E, Indolfi G. Treatment of chronic hepatitis B infection in infants and young children: A systematic review. World J Hepatol 2026; 18(4): 116657
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| URL |
https://www.wjgnet.com/1948-5182/full/v18/i4/116657.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v18.i4.116657 |
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