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Publication Name World Journal of Cardiology
Manuscript ID 116661
Country Japan
Received
2025-11-17 10:58
Peer-Review Started
2025-11-17 10:58
First Decision by Editorial Office Director
2025-11-26 08:19
Return for Revision
2025-11-26 08:19
Revised
2025-12-09 21:16
Publication Fee Transferred
Second Decision by Editor
2026-01-23 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-23 06:03
Articles in Press
2026-01-23 06:03
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-13 02:59
Publish the Manuscript Online
2026-03-23 08:54
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Retrospective Study
Article Title Prognostic significance of vascular endothelial dysfunction in patients with vasospastic angina
Manuscript Source Unsolicited Manuscript
All Author List Hiroki Teragawa, Yu Hashimoto, Akane Tsuchiya and Shuichi Nomura
ORCID
Author(s) ORCID Number
Hiroki Teragawa http://orcid.org/0000-0002-0183-2541
Yu Hashimoto http://orcid.org/0000-0001-5741-6734
Akane Tsuchiya http://orcid.org/0000-0001-8995-4721
Shuichi Nomura http://orcid.org/0009-0002-5045-6690
Funding Agency and Grant Number
Corresponding Author Hiroki Teragawa, Department of Cardiovascular Medicine, Futabanosato Prefectural Hospital, 3-1-36 Futabanosato, Higashi-ku, Hiroshima 732-0057, Japan. hiroki-teragawa@jrhh.or.jp
Key Words Coronary spasm; Endothelial function; Flow-mediated dilatation; Focal spasm; Vasospastic angina; Vascular endothelial dysfunction
Core Tip Vasospastic angina usually carries a favorable prognosis with lifestyle modification and vasodilator therapy, but reliable noninvasive prognostic markers remain scarce. This study examined whether vascular endothelial dysfunction, assessed by brachial artery flow-mediated dilation, could serve as a marker. Patients with lower flow-mediated dilation values (< 3.7%) had worse outcomes, indicating that vascular endothelial dysfunction is associated with poorer prognosis in vasospastic angina. These findings highlight the potential role of endothelial function assessment in risk stratification, warranting further validation in larger studies.
Publish Date 2026-03-23 08:54
Citation

Teragawa H, Hashimoto Y, Tsuchiya A, Nomura S. Prognostic significance of vascular endothelial dysfunction in patients with vasospastic angina. World J Cardiol 2026; 18(3): 116661

URL https://www.wjgnet.com/1949-8462/full/v18/i3/116661.htm
DOI https://dx.doi.org/10.4330/wjc.v18.i3.116661
Full Article (PDF) WJC-18-116661-with-cover.pdf
Manuscript File 116661_Auto_Edited_102149.docx
Answering Reviewers 116661-answering-reviewers.pdf
Audio Core Tip 116661-audio.m4a
Biostatistics Review Certificate 116661-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 116661-conflict-of-interest-statement.pdf
Copyright License Agreement 116661-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 116661-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 116661-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 116661-non-native-speakers.pdf
Peer-review Report 116661-peer-reviews.pdf
Scientific Misconduct Check 116661-scientific-misconduct-check.png
Scientific Editor Work List 116661-scientific-editor-work-list.pdf
CrossCheck Report 116661-crosscheck-report.pdf