Publication Name	World Journal of Gastroenterology
Manuscript ID	11676
Country	Canada

Received	2014-05-29 17:35
Peer-Review Started	2014-05-30 00:03
To Make the First Decision	2014-07-21 13:37
Return for Revision	2014-07-28 14:11
Revised	2014-08-23 02:21
Second Decision	2014-10-15 07:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-10-15 08:08
Articles in Press	2014-10-15 08:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-11-21 11:36
Publish the Manuscript Online	2014-12-10 15:52

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Non-invasive diagnosis of advanced fibrosis and cirrhosis
Manuscript Source	Invited Manuscript
All Author List	Suraj Sharma, Korosh Khalili and Geoffrey Christopher Nguyen
Funding Agency and Grant Number
Corresponding Author	Geoffrey Christopher Nguyen, MD, PhD, FRCPC, Joseph and Wolf Lebovic Health Complex, Mount Sinai Hospital, 437-600 University Avenue, Toronto, ON M5G 1X5, Canada. geoff.nguyen@utoronto.ca
Key Words	Cirrhosis; Biomarker; Non-invasive; Fibrosis; Viral; Non-alcoholic fatty liver disease; Primary biliary cirrhosis; Autoimmune hepatitis; Hepatitis B virus; Hepatitis C virus
Core Tip	There has been considerable research in recent years towards the development of non-invasive markers of cirrhosis. These include novel radiologic techniques, serum biomarkers and panels of fibrosis. In this review, we outline the current state of knowledge on the most commonly used radiologic and serum biomarkers of cirrhosis. The pathophysiologic principles behind the use of these markers are discussed. In addition, we focus on the evidence behind the use of these markers, and highlight their performance characteristics. This review is intended to provide an overview of the current knowledge in this area, and to encapsulate the evidence for the reader.
Publish Date	2014-12-10 15:52
Citation	Sharma S, Khalili K, Nguyen GC. Non-invasive diagnosis of advanced fibrosis and cirrhosis. World J Gastroenterol 2014; 20(45): 16820-16830
URL	http://www.wjgnet.com/1007-9327/full/v20/i45/16820.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i45.16820

Full Article (PDF)	WJG-20-16820.pdf
Full Article (Word)	WJG-20-16820.doc
Manuscript File	11676-Review.docx
Answering Reviewers	11676-Answering reviewers.pdf
Copyright License Agreement	11676-Copyright assignment.pdf
Peer-review Report	11676-Peer review(s).pdf
Scientific Misconduct Check	11676-CrossCheck.jpg
Scientific Editor Work List	11676-Scientific editor work list.pdf