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Articles Published Processes
4/17/2026 7:16:57 AM | Browse: 58 | Download: 152
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Received |
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2025-11-26 03:02 |
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Peer-Review Started |
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2025-11-26 03:02 |
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First Decision by Editorial Office Director |
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2025-12-17 10:08 |
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Return for Revision |
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2025-12-17 10:08 |
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Revised |
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2025-12-31 11:42 |
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Publication Fee Transferred |
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2026-01-04 05:30 |
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Second Decision by Editor |
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2026-01-28 02:43 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-28 07:30 |
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Articles in Press |
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2026-01-28 07:30 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-07 03:25 |
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Publish the Manuscript Online |
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2026-04-17 07:16 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Effectiveness of ustekinumab in postoperative Crohn's disease management: Evidence from a Chinese multicenter cohort
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xian-Zong Ma, Xing-Zhao Han, Wen-Yu Zhang, Feng Tian, Xu-Chun Zhou, Lin-Yan Zhou, Yong-Sheng Teng, Ling Lei, Jian-Qiu Sheng, Peng Jin, Xin-Mei Zhao and Yan Jia |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Capital Health Development Scientific Research Project |
2018-1-5091 |
| National Natural Science Foundation of China |
82500685 |
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| Corresponding Author |
Yan Jia, Professor, Department of Gastroenterology, The Seventh Medical Center of Chinese PLA General Hospital, No.5 Nanmencang, Dongcheng District, Beijing 100700, China. jiayan328@163.com |
| Key Words |
Crohn's disease; Ustekinumab; Postoperative recurrence; Rutgeerts score; Endoscopic improvement |
| Core Tip |
This multicenter study demonstrated that ustekinumab (UST) effectively addressed the management of postoperative recurrence in patients with Crohn's disease in China. Results showed high rates of endoscopic (81.7%) and clinical remission (91.5%) at 24 weeks. A multivariate analysis identified first-line UST use and shorter disease duration as independent predictors of superior outcomes. The favorable safety profile supports UST as a potent therapeutic option, particularly when initiated early as a first-line biologic strategy for postoperative management. |
| Publish Date |
2026-04-17 07:16 |
| Citation |
Ma XZ, Han XZ, Zhang WY, Tian F, Zhou XC, Zhou LY, Teng YS, Lei L, Sheng JQ, Jin P, Zhao XM, Jia Y. Effectiveness of ustekinumab in postoperative Crohn's disease management: Evidence from a Chinese multicenter cohort. World J Gastroenterol 2026; 32(16): 116781 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i16/116781.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i16.116781 |
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