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Publication Name World Journal of Gastroenterology
Manuscript ID 116783
Country Italy
Received
2025-11-21 05:20
Peer-Review Started
2025-11-21 05:21
First Decision by Editorial Office Director
2026-01-07 09:20
Return for Revision
2026-01-07 09:20
Revised
2026-01-09 14:34
Publication Fee Transferred
2026-02-03 18:19
Second Decision by Editor
2026-03-26 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-26 08:34
Articles in Press
2026-03-26 08:34
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-24 07:31
Publish the Manuscript Online
2026-06-30 13:35
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pathology
Manuscript Type Case Report
Article Title Abdominal nodular histiocytic/mesothelial hyperplasia - intraoperative pitfalls, differential diagnosis, literature review: A case report
Manuscript Source Unsolicited Manuscript
All Author List Piergiuseppe Colombo, Giulia Dani, Benedetta Saracini, Carlo Castoro and Paola Spaggiari
ORCID
Author(s) ORCID Number
Piergiuseppe Colombo http://orcid.org/0000-0002-6161-6138
Carlo Castoro http://orcid.org/0000-0001-9601-9336
Paola Spaggiari http://orcid.org/0000-0002-7544-957X
Funding Agency and Grant Number
Corresponding Author Piergiuseppe Colombo, Associate Professor, Department of Biomedical Science, Humanitas University, Via Rita Levi Montalcini, 4, Pieve Emanuele, Milan 20072, Italy. piergiuseppe.colombo@hunimed.eu
Key Words Nodular histiocytic hyperplasia; Mesothelial hyperplasia; Nodular histiocytic/mesothelial hyperplasia; Peritoneum; Frozen section; Mesothelial cells; Pitfall; Carcinomatosis; Gastric adenocarcinoma; Case report
Core Tip Nodular histiocytic/mesothelial hyperplasia is a rare benign lesion that may mimic peritoneal dissemination of malignancy, especially during frozen-section examination. This case emphasizes the diagnostic pitfalls arising from its histologic resemblance to metastatic carcinoma and highlights how coexistence with true metastatic implants increases the risk of misinterpretation. Few reports describe concurrent metastatic carcinoma and nodular histiocytic/mesothelial hyperplasia, making intraoperative differentiation particularly challenging. Knowledge of its characteristic morphology and immunoprofile is crucial for surgeons and pathologists.
Publish Date 2026-06-30 13:35
Citation

Colombo P, Dani G, Saracini B, Castoro C, Spaggiari P. Abdominal nodular histiocytic/mesothelial hyperplasia - intraoperative pitfalls, differential diagnosis, literature review: A case report. World J Gastroenterol 2026; 32(25): 116783

URL https://www.wjgnet.com/1007-9327/full/v32/i25/116783.htm
DOI https://doi.org/10.3748/wjg.116783
Full Article (PDF) WJG-32-116783-with-cover.pdf
CARE Checklist–2016 116783-CARE-Checklist-2016.pdf
Manuscript File 116783_Auto_Edited_130717.docx
Answering Reviewers 116783-answering-reviewers.pdf
Audio Core Tip 116783-audio.m4a
Conflict-of-Interest Disclosure Form 116783-conflict-of-interest-statement.pdf
Copyright License Agreement 116783-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 116783-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 116783-non-native-speakers.pdf
Peer-review Report 116783-peer-reviews.pdf
Scientific Misconduct Check 116783-scientific-misconduct-check.png
Scientific Editor Work List 116783-scientific-editor-work-list.pdf
CrossCheck Report 116783-crosscheck-report.pdf