Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	1168
Country	Thailand

Received	2012-11-17 05:33
Peer-Review Started	2012-11-19 15:59
To Make the First Decision	2013-02-01 21:38
Return for Revision	2013-02-06 17:23
Revised	2013-03-05 23:34
Second Decision	2013-03-15 18:06
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-03-15 23:23
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-04-09 16:44
Publish the Manuscript Online	2013-05-02 10:45

ISSN	1948-5204 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Autobiography
Article Title	Prognostic factors in resectable cholangiocarcinoma patients: Carcinoembryonic antigen, lymph node, surgical margin and chemotherapy
Manuscript Source	Invited Manuscript
All Author List	Kosin Wirasorn, Thundon Ngamprasertchai, Jarin Chindaprasirt, Aumkhae Sookprasert, Narong Khantikaew, Ake Pakkhem and Piti Ungarereevittaya
Funding Agency and Grant Number	Funding Agency Grant Number Khon Kaen University Publication Clinic, Research
Corresponding Author	Kosin Wirasorn, MD, Department of Medicine, Khon Kaen University, Amphur Muang, 40002 Khon Kaen, Thailand. wkosin@kku.ac.th
Key Words	Cholangiocarcinoma; Prognosis; Carcinoembryonic antigen; Lymph nodes; Neoplasm metastasis; Surgical margin status; Hepatectomy; Chemotherapy; Adjuvant; Survival rate
Core Tip	Cholangiocarcinoma has a high prevalence in the Asian countries, particularly Thailand. Cholangiocarcinoma patients usually have a high mortality rate and poor treatment outcomes. Curative surgery is the only treatment for early stages of this cancer. Cholangiocarcinoma has a high rate of recurrence. This study aimed to evaluate outcomes in resectable cholangiocarcinoma patients and to determine prognostic factors. The results demonstrated serum carcinoembryonic antigen and lymph node metastases which were associated with advanced stage tumors become strong negative prognostic factors in cholangiocarcinoma, while additional treatment including adjuvant chemotherapy and adequate surgical resection may improve survival time.
Publish Date	2013-05-02 10:45
Citation	Wirasorn K, Ngamprasertchai T, Chindaprasirt J, Sookprasert A, Khantikaew N, Pakkhem A, Ungarereevittaya P. Prognostic factors in resectable cholangiocarcinoma patients: Carcinoembryonic antigen, lymph node, surgical margin and chemotherapy. World J Gastrointest Oncol 2012; 5(4): 81-87
URL	http://www.wjgnet.com/1948-5204/full/v5/i4/81.htm
DOI	http://dx.doi.org/10.4251/wjgo.v5.i4.81

Full Article (PDF)	WJGO-5-81.pdf
Manuscript File	1168-Review.doc
Answering Reviewers	1168-Answering reviewers.pdf
Copyright License Agreement	1168-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	1168-Language certificate.pdf
Peer-review Report	1168-Peer reviews.docx
Scientific Editor Work List	1168-Scientific editor work list.doc