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5/27/2026 1:22:01 PM | Browse: 1 | Download: 1
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 116822
Country China
Received
2025-11-21 07:52
Peer-Review Started
2025-11-21 07:53
First Decision by Editorial Office Director
2025-12-11 07:56
Return for Revision
2025-12-11 07:56
Revised
2025-12-23 11:35
Publication Fee Transferred
2025-12-26 06:11
Second Decision by Editor
2026-02-10 02:48
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-10 03:27
Articles in Press
2026-02-10 03:27
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-13 02:58
Publish the Manuscript Online
2026-05-27 13:22
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Visceral obesity exacerbates perioperative muscle loss and impairs survival in colorectal cancer
Manuscript Source Unsolicited Manuscript
All Author List Yun Wang, Jun Bu, Chen-Yang Zhan, Da-Lin Xu, Jia-Qi Hu, Ming-Hao Zhang, Ke-Jin Zhu and Yang Qi
ORCID
Author(s) ORCID Number
Yun Wang http://orcid.org/0009-0008-7941-5466
Jun Bu http://orcid.org/0000-0002-3636-6253
Funding Agency and Grant Number
Corresponding Author Jun Bu, Chief Physician, MD, PhD, Department of General Surgery, Sichuan University Affiliated Chengdu Second People’s Hospital, No. 10 Qingyun South Street, Jinjiang District, Chengdu 610021, Sichuan Province, China. bj_227688@126.com
Key Words Colorectal cancer; Visceral fat; Skeletal muscle loss; Sarcopenic obesity; Prognosis
Core Tip This study identifies high visceral fat area as an independent driver of perioperative skeletal muscle loss and poor survival in colorectal cancer. Using dynamic computed tomography monitoring, we demonstrate that visceral obesity exacerbates muscle wasting through chronic inflammation. Paradoxically, higher preoperative muscle mass increased skeletal muscle loss risk, potentially indicating underlying myosteatosis. These findings redefine the fat-muscle axis in cancer prognosis and highlight the critical need for preoperative body composition assessment to guide metabolic interventions and improve long-term outcomes.
Publish Date 2026-05-27 13:22
Citation

Wang Y, Bu J, Zhan CY, Xu DL, Hu JQ, Zhang MH, Zhu KJ, Qi Y. Visceral obesity exacerbates perioperative muscle loss and impairs survival in colorectal cancer. World J Gastrointest Surg 2026; 18(5): 116822

URL https://www.wjgnet.com/1948-9366/full/v18/i5/116822.htm
DOI https://dx.doi.org/10.4240/wjgs.v18.i5.116822
Full Article (PDF) WJGS-18-116822-with-cover.pdf
STROBE Statement 116822-STROBE-statement.pdf
Manuscript File 116822_Auto_Edited_021348-YJP.docx
Answering Reviewers 116822-answering-reviewers.pdf
Audio Core Tip 116822-audio.mp3
Biostatistics Review Certificate 116822-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 116822-conflict-of-interest-statement.pdf
Copyright License Agreement 116822-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 116822-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 116822-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 116822-non-native-speakers.pdf
Peer-review Report 116822-peer-reviews.pdf
Scientific Misconduct Check 116822-scientific-misconduct-check.png
Scientific Editor Work List 116822-scientific-editor-work-list.pdf
CrossCheck Report 116822-crosscheck-report.pdf