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Articles Published Processes
3/23/2026 8:21:10 AM | Browse: 0 | Download: 0
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Received |
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2025-11-21 05:15 |
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Peer-Review Started |
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2025-11-21 05:15 |
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First Decision by Editorial Office Director |
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2025-12-03 09:52 |
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Return for Revision |
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2025-12-04 05:56 |
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Revised |
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2025-12-17 12:54 |
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Publication Fee Transferred |
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2025-12-24 11:57 |
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Second Decision by Editor |
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2026-01-26 02:57 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-26 14:46 |
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Articles in Press |
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2026-01-26 14:46 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-16 03:15 |
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Publish the Manuscript Online |
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2026-03-23 08:21 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Exosomes in cancer: Functional mechanisms and therapeutic perspectives
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Wei-Zhang Xiao and Jia-Hai Shi |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Jiangsu Provincial Research Hospital |
YJXYY202204 |
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| Corresponding Author |
Wei-Zhang Xiao, Assistant Professor, Department of Cardiothoracic Surgery, Affiliated Hospital and Medical School of Nantong University, No. 20 Xisi Road, Chongchuan District, Nantong 226001, Jiangsu Province, China. xwz191201@163.com |
| Key Words |
Exosomes; Cancer therapy; Drug delivery; Immunomodulation; Mesenchymal stem cells; Tumor microenvironment |
| Core Tip |
This minireview elucidates the triple roles of exosomes in cancer therapy: As direct effectors, drug delivery vehicles, and immunomodulators. Focusing on mesenchymal stem cell-derived exosomes as a paradigm, it details their context-dependent, “double-edged sword” functionality in tumor regulation. The discussion extends to key translational challenges, including cargo complexity and manufacturing standardization, while highlighting engineering strategies as the critical path toward harnessing exosomes as potent, cell-free therapeutics. |
| Publish Date |
2026-03-23 08:21 |
| Citation |
Xiao WZ, Shi JH. Exosomes in cancer: Functional mechanisms and therapeutic perspectives. World J Clin Oncol 2026; 17(3): 116823 |
| URL |
https://www.wjgnet.com/2218-4333/full/v17/i3/116823.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v17.i3.116823 |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
