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Publication Name World Journal of Gastroenterology
Manuscript ID 116837
Country South Korea
Received
2025-11-24 10:41
Peer-Review Started
2025-11-24 10:41
First Decision by Editorial Office Director
2026-01-22 08:51
Return for Revision
2026-01-22 08:51
Revised
2026-01-23 13:47
Publication Fee Transferred
2026-01-27 02:47
Second Decision by Editor
2026-02-27 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-27 07:38
Articles in Press
2026-02-27 07:38
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-29 02:56
Publish the Manuscript Online
2026-05-18 10:29
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Retrospective Study
Article Title Rescue liver transplantation for liver failure with extrahepatic metastases: An ethical and clinical framework informed by two cases
Manuscript Source Unsolicited Manuscript
All Author List Seoung Hoon Kim, Byoung Ho An, Jin A Lee and Go Woon Jeong
ORCID
Author(s) ORCID Number
Seoung Hoon Kim http://orcid.org/0000-0001-7921-1801
Byoung Ho An http://orcid.org/0009-0000-4919-7594
Jin A Lee http://orcid.org/0009-0009-7008-0097
Go Woon Jeong http://orcid.org/0000-0002-7244-8969
Funding Agency and Grant Number
Corresponding Author Seoung Hoon Kim, MD, Senior Researcher, Organ Transplantation Center, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang 10408, Gyeonggi-do, South Korea. kshlj@hanmail.net
Key Words Liver transplantation; Extrahepatic metastases; Hepatic failure; Contraindications; Surgical ethics
Core Tip Rescue liver transplantation (LT) is generally considered futile in patients with extrahepatic metastases, yet in rare situations acute liver failure not tumor progression poses the true immediate threat to life. This study describes two such exceptional cases and proposes a structured ethical-clinical decision framework integrating futility assessment, donor safety, allocation fairness, and values-aligned consent. Our model outlines when rescue LT may be ethically and clinically defensible, emphasizing that its value lies in restoring hepatic function and providing meaningful time not oncologic cure.
Publish Date 2026-05-18 10:29
Citation

Kim SH, An BH, Lee JA, Jeong GW. Rescue liver transplantation for liver failure with extrahepatic metastases: An ethical and clinical framework informed by two cases. World J Gastroenterol 2026; 32(19): 116837

URL https://www.wjgnet.com/1007-9327/full/v32/i19/116837.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i19.116837
Full Article (PDF) WJG-32-116837-with-cover.pdf
Manuscript File 116837_Auto_Edited_015235.docx
Answering Reviewers 116837-answering-reviewers.pdf
Audio Core Tip 116837-audio.mp3
Biostatistics Review Certificate 116837-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 116837-conflict-of-interest-statement.pdf
Copyright License Agreement 116837-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 116837-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 116837-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 116837-non-native-speakers.pdf
Peer-review Report 116837-peer-reviews.pdf
Scientific Misconduct Check 116837-scientific-misconduct-check.png
Scientific Editor Work List 116837-scientific-editor-work-list.pdf
CrossCheck Report 116837-crosscheck-report.pdf