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Articles Published Processes
6/15/2026 8:38:28 AM | Browse: 2 | Download: 1
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Received |
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2025-11-24 04:21 |
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Peer-Review Started |
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2025-11-24 04:21 |
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First Decision by Editorial Office Director |
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2025-12-17 09:31 |
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Return for Revision |
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2025-12-17 09:31 |
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Revised |
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2025-12-21 21:13 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-02 02:45 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-03 01:05 |
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Articles in Press |
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2026-02-03 01:05 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-06-01 23:51 |
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Publish the Manuscript Online |
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2026-06-15 08:38 |
| ISSN |
2220-6124 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Urology & Nephrology |
| Manuscript Type |
Case Control Study |
| Article Title |
Alpha-1-microglobulin as an early biomarker in renal extrahepatic manifestations of hepatitis C virus infection
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Enas A R Alkareemy, Nashwa M Azoz, Ghada S Abdelnaiem, Rabea A Gadelkareem, Kawsar A Saleh and Essam M Abdel Aziz |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Rabea A Gadelkareem, Department of Urology, Assiut Urology and Nephrology Hospital, Faculty of Medicine, Assiut University, Elgamaa Street, Assiut 71515, Egypt. rabeagad@aun.edu.eg |
| Key Words |
Alpha-1-microglobulin; Hepatitis C virus; Kidney injury; Renal extrahepatic manifestations; Urinary biomarkers |
| Core Tip |
Chronic hepatitis C virus (HCV) infection can lead to subclinical renal injury that often progresses unnoticed until chronic kidney disease develops. In this study, urinary alpha-1-microglobulin (Uα1M) proved to be a sensitive, early, and non-invasive biomarker for detecting tubular dysfunction in HCV-infected patients. The rate of elevated Uα1M levels correlated with subtle renal alterations and demonstrated strong diagnostic accuracy, even when traditional renal markers were within normal limits. Routine Uα1M assessment may facilitate early detection and intervention for HCV-related renal involvement, improving long-term renal outcomes. |
| Publish Date |
2026-06-15 08:38 |
| Citation |
Alkareemy EAR, Azoz NM, Abdelnaiem GS, Gadelkareem RA, Saleh KA, Abdel Aziz EM. Alpha-1-microglobulin as an early biomarker in renal extrahepatic manifestations of hepatitis C virus infection. World J Nephrol 2026; 15(2): 116866
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| URL |
https://www.wjgnet.com/2220-6124/full/v15/i2/116866.htm |
| DOI |
https://doi.org/10.5527/wjn.v15.i2.116866 |
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