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Articles Published Processes
5/14/2026 9:17:10 AM | Browse: 4 | Download: 22
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Received |
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2025-11-24 03:22 |
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Peer-Review Started |
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2025-11-24 05:40 |
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First Decision by Editorial Office Director |
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2026-01-08 02:58 |
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Return for Revision |
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2026-01-08 02:58 |
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Revised |
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2026-01-12 07:47 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-11 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-11 06:14 |
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Articles in Press |
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2026-02-11 06:14 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-28 00:14 |
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Publish the Manuscript Online |
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2026-05-14 09:17 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Opinion Review |
| Article Title |
Inhibiting exosomal miR-191 can induce ferroptosis in macrophages, thereby delaying the progression of colorectal cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Zi-Wei Wang, Li Jia, Ling-Ke Qu and Guo-Hua Gong |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Guo-Hua Gong, Professor, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, No. 82 West College Road, Wenzhou 325035, Zhejiang Province, China. guohgong@wmu.edu.cn |
| Key Words |
MicroRNA-191; Ferroptosis; Reactive oxygen species; Macrophage; Inflammation |
| Core Tip |
Inhibiting miR-191 effectively suppresses macrophage M2 polarization by inducing the production of reactive oxygen species in CRC cells, triggering ferroptosis and subsequent apoptosis. Exosomal miR-191 may become a potential therapeutic target with significant implications for achieving precise diagnosis, precise treatment, and early disease prevention. |
| Publish Date |
2026-05-14 09:17 |
| Citation |
Wang ZW, Jia L, Qu LK, Gong GH. Inhibiting exosomal miR-191 can induce ferroptosis in macrophages, thereby delaying the progression of colorectal cancer. World J Gastrointest Oncol 2026; 18(5): 116881 |
| URL |
https://www.wjgnet.com/1948-5204/full/v18/i5/116881.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v18.i5.116881 |
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