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Articles Published Processes
6/22/2026 8:41:00 AM | Browse: 3 | Download: 2
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Received |
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2025-11-24 05:46 |
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Peer-Review Started |
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2025-11-24 05:46 |
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First Decision by Editorial Office Director |
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2025-12-03 08:00 |
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Return for Revision |
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2025-12-06 15:29 |
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Revised |
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2025-12-16 11:03 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-02 02:52 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-02 13:33 |
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Articles in Press |
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2026-02-02 13:33 |
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Edit the Manuscript by Language Editor |
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2026-02-05 17:40 |
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Typeset the Manuscript |
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2026-06-10 08:19 |
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Publish the Manuscript Online |
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2026-06-22 08:41 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Correspondence |
| Article Title |
Yin Yang 1 in inflammatory memory and progression susceptibility in Helicobacter pylori–associated gastric cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Meng-Fan Wei |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Meng-Fan Wei, Zhejiang Chinese Medical University, School of Medical Technology and Information Engineering, Puyan Street, Binjiang District, Hangzhou City, Zhejiang Province Binwen Campus of Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China. 202312210701027@zcmu.edu.cn |
| Key Words |
Helicobacter pylori; Gastric cancer; Yin Yang 1; Janus kinase 2-signal transducer and activator of transcriptional protein 3 signaling; Epithelial-mesenchymal transition; Inflammatory memory; Progression susceptibility; Epigenetic imprinting |
| Core Tip |
This commentary discusses the study by Chen et al, which demonstrated that Yin Yang 1 (YY1) mediates Helicobacter pylori (H. pylori)-induced activation of the Janus kinase 2-signal transducer and activator of transcriptional protein 3 pathway and epithelial-mesenchymal transition in gastric cancer. By Integrating recent work on innate and epithelial inflammatory memory with the broader biology of YY1 in malignancy, this article propose that sustained and heterogeneous upregulation of YY1 upregulation may represent an inflammation-derived transcriptional imprint and an early determinant of progression susceptibility. These insights open new directions for risk stratification and pathway-targeted prevention in H. pylori-infected individuals. |
| Publish Date |
2026-06-22 08:41 |
| Citation |
Wei MF. Yin Yang 1 in inflammatory memory and progression susceptibility in Helicobacter pylori–associated gastric cancer. World J Clin Oncol 2026; 17(6): 116895
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| URL |
https://www.wjgnet.com/2218-4333/full/v17/i6/116895.htm |
| DOI |
https://doi.org/10.5306/wjco.116895 |
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