| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Outcomes of pediatric liver transplant recipients who reach adulthood: Current perspectives and unmet needs
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Alberto Ferrarese, Mara Cananzi, Luca Bosa, Marco Senzolo, Giacomo Germani, Laura Marta Vivian, Claudia Mescoli, Annalisa Dolcet, Enrico Gringeri, Lorenzo D’Antiga, Marco Spada, Jorge Amil Dias, Umberto Cillo and Patrizia Burra |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Alberto Ferrarese, Multivisceral Transplant Unit, Department of Surgery, Oncology and Gastroenterology, Padova University Hospital, Via Giustiniani 2, Padova 35122, Veneto, Italy. alberto.ferrarese@unipd.it |
| Key Words |
Adherence; Allograft rejection; Chronic kidney disease; Transition; Long-term outcomes |
| Core Tip |
Pediatric liver transplantation has progressed from a life-saving procedure to one offering excellent long-term survival, with most recipients reaching adulthood. The focus has shifted from survival to global health which encompasses medical outcomes, psychological well-being, social integration, quality of life, and long-term functional and developmental success. However, only a minority achieve the ideal outcome, largely due to medical complications. Graft-related issues (such as persistent liver function test abnormalities) and extrahepatic complications, including chronic kidney disease, metabolic disorders, and de novo cancers, often result from long-term immunosuppression. This minireview highlights determinants of long-term outcomes and proposes refinements to better assess the ideal outcome. |
| Publish Date |
2026-05-06 08:34 |
| Citation |
Ferrarese A, Cananzi M, Bosa L, Senzolo M, Germani G, Vivian LM, Mescoli C, Dolcet A, Gringeri E, D’Antiga L, Spada M, Dias JA, Cillo U, Burra P. Outcomes of pediatric liver transplant recipients who reach adulthood: Current perspectives and unmet needs. World J Gastroenterol 2026; 32(18): 116902 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i18/116902.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i18.116902 |
