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Publication Name World Journal of Methodology
Manuscript ID 116914
Country China
Received
2025-11-25 03:19
Peer-Review Started
2025-11-25 03:41
First Decision by Editorial Office Director
2026-01-06 06:26
Return for Revision
2026-01-06 11:51
Revised
2026-01-09 09:45
Publication Fee Transferred
Second Decision by Editor
2026-01-22 02:33
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-22 05:49
Articles in Press
2026-01-22 05:49
Edit the Manuscript by Language Editor
2026-01-24 04:51
Typeset the Manuscript
2026-06-25 10:01
Publish the Manuscript Online
2026-07-10 10:11
ISSN 2222-0682 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Correspondence
Article Title Letter to the Editor: Low-energy fractional carbon dioxide laser priming of mesenchymal stem cell-derived exosomes: A photothermal boost for diabetic wound angiogenesis
Manuscript Source Unsolicited Manuscript
All Author List Xu-Jin Wu, Ju-Yu Tang and Nian-Zhe Sun
ORCID
Author(s) ORCID Number
Nian-Zhe Sun http://orcid.org/0000-0001-7660-110X
Funding Agency and Grant Number
Corresponding Author Nian-Zhe Sun, MD, PhD, National Clinical Research Center of Geriatric Disorders, Xiangya Hospital, Central South University, 87 Xiangya Road, Kaifu District, Changsha, Hunan, Changsha 410008, Hunan Province, China. sunnzh201921@sina.com
Key Words Diabetic wound; Fractional carbon dioxide laser; Photothermal preconditioning; Sphingosine-1-phosphate; Acellular therapy
Core Tip Chen et al demonstrate that fractional carbon dioxide laser-induced photothermal stimulation enhances the biological activity of mesenchymal stem cell-derived exosomes by enriching sphingosine-1-phosphate content and activating the S1PR1/AKT/HIF-1α pathway. These laser-activated exosomes significantly promote endothelial angiogenesis and accelerate diabetic wound healing in vivo. This study introduces a safe, controllable, and clinically accessible strategy for optimizing exosome-based acellular therapies in chronic diabetic wounds.
Publish Date 2026-07-10 10:11
Citation

Wu XJ, Tang JY, Sun NZ. Letter to the Editor: Low-energy fractional carbon dioxide laser priming of mesenchymal stem cell-derived exosomes: A photothermal boost for diabetic wound angiogenesis. World J Methodol 2026; 16(3): 116914

URL https://www.wjgnet.com/2222-0682/full/v16/i3/116914.htm
DOI https://doi.org/10.5662/wjm.116914
Full Article (PDF) WJM-16-116914-with-cover.pdf
Manuscript File 116914_Auto_Edited_084136.docx
Answering Reviewers 116914-answering-reviewers.pdf
Audio Core Tip 116914-audio.m4a
Conflict-of-Interest Disclosure Form 116914-conflict-of-interest-statement.pdf
Copyright License Agreement 116914-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 116914-non-native-speakers.pdf
Peer-review Report 116914-peer-reviews.pdf
Scientific Misconduct Check 116914-scientific-misconduct-check.png
Scientific Editor Work List 116914-scientific-editor-work-list.pdf
CrossCheck Report 116914-crosscheck-report.pdf