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Publication Name World Journal of Virology
Manuscript ID 116939
Country Türkiye
Received
2025-11-25 03:52
Peer-Review Started
2025-11-25 03:52
First Decision by Editorial Office Director
2026-01-07 08:42
Return for Revision
2026-01-07 08:42
Revised
2026-01-16 15:57
Publication Fee Transferred
Second Decision by Editor
2026-02-10 02:45
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-10 10:08
Articles in Press
2026-02-10 10:08
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-11 01:10
Publish the Manuscript Online
2026-03-13 08:28
ISSN 2220-3249 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Minireviews
Article Title Next-generation mucosal vaccines for respiratory viruses: Immunological correlates, platform design and clinical translation
Manuscript Source Invited Manuscript
All Author List Salma Younas, Soha Farooq, Sweta Sahu, Rhobi Peter Mwita and Öner Özdemir
ORCID
Author(s) ORCID Number
Öner Özdemir http://orcid.org/0000-0002-5338-9561
Funding Agency and Grant Number
Corresponding Author Öner Özdemir, MD, Professor, Department of Pediatric Allergy and Immunology, Faculty of Medical, Sakarya University, Adnan Menderes Cad, Adapazarı 54100, Sakarya, Türkiye. ozdemir_oner@hotmail.com
Key Words Mucosal vaccines; Secretory IgA; Tissue-resident memory T lymphocytes; Intranasal vaccination; Respiratory viruses; Vaccine platforms; Immune correlates
Core Tip Respiratory viruses initiate infections at mucosal surfaces; however, most licensed vaccines induce predominantly systemic immunity. Next-generation mucosal vaccines aim to generate protective immunity directly at the point of viral entry by inducing secretory IgA, tissue-resident memory T lymphocytes, and rapid innate immune responses in the respiratory tract. This review integrates key mucosal immune correlates with vaccine platform design, delivery strategies, and the emerging clinical evidence. We highlight the translational challenges and practical approaches.
Publish Date 2026-03-13 08:28
Citation

Younas S, Farooq S, Sahu S, Mwita RP, Özdemir Ö. Next-generation mucosal vaccines for respiratory viruses: Immunological correlates, platform design and clinical translation. World J Virol 2026; 15(1): 116939

URL https://www.wjgnet.com/2220-3249/full/v15/i1/116939.htm
DOI https://dx.doi.org/10.5501/wjv.v15.i1.116939
Full Article (PDF) WJV-15-116939-with-cover.pdf
Manuscript File 116939_Auto_Edited_080636.docx
Answering Reviewers 116939-answering-reviewers.pdf
Audio Core Tip 116939-audio.mp4
Conflict-of-Interest Disclosure Form 116939-conflict-of-interest-statement.pdf
Copyright License Agreement 116939-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 116939-non-native-speakers.pdf
Peer-review Report 116939-peer-reviews.pdf
Scientific Misconduct Check 116939-scientific-misconduct-check.png
Scientific Editor Work List 116939-scientific-editor-work-list.pdf
CrossCheck Report 116939-crosscheck-report.pdf