| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Behavioral Sciences |
| Manuscript Type |
Prospective Study |
| Article Title |
Upper gastrointestinal endoscopic screening serves as a primary prevention approach by reducing modifiable risk factors
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiang-Wen Cheng, Zhen Liu, Chuan-Hai Guo, Feng-Lei Li, Ya-Qi Pan, Ying Liu, Fang-Fang Liu, Huan-Yu Chen, Wen-Lei Yang, Hong-Rui Tian, Chao Shi, Zhong-Hu He, Meng-Fei Liu and Yang Ke |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Key R&D Program of Ningxia Hui Autonomous Region |
No. 2025BEG01011 |
| Science and Technology Plan of Tibet Autonomous Region |
No. XZ202501JD0021 |
|
| Corresponding Author |
Meng-Fei Liu, PhD, Professor, Department of Genetics, Peking University Cancer Hospital, No. 52 Fucheng Road, Haidian District, Beijing 100142, Beijing, China. liumengfei1205@foxmail.com |
| Key Words |
Upper gastrointestinal tract cancer; Endoscopic screening; Risk factors; Primary prevention; Health promotion |
| Core Tip |
This study provides novel evidence that upper gastrointestinal (UGI) endoscopic screening contributes to primary cancer prevention by reducing modifiable risk factors. Based on a population-based randomized controlled trial, we showed that UGI screening significantly promoted the reduction of cigarette smoking, alcohol drinking, and unhealthy dietary habits, particularly among women and older adults. These findings highlight the potential of UGI endoscopic screening to modify behavioral risk factors at the population level, underscoring its broader preventive value in cancer control strategies. Integrating health education into UGI screening programs may further enhance its effectiveness in reducing the cancer burden. |
| Publish Date |
2026-04-08 07:28 |
| Citation |
Cheng XW, Liu Z, Guo CH, Li FL, Pan YQ, Liu Y, Liu FF, Chen HY, Yang WL, Tian HR, Shi C, He ZH, Liu MF, Ke Y. Upper gastrointestinal endoscopic screening serves as a primary prevention approach by reducing modifiable risk factors. World J Gastrointest Oncol 2026; 18(4): 116949 |
| URL |
https://www.wjgnet.com/1948-5204/full/v18/i4/116949.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v18.i4.116949 |
