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Articles Published Processes
4/17/2026 7:17:00 AM | Browse: 4 | Download: 10
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Received |
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2025-11-28 01:09 |
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Peer-Review Started |
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2025-11-28 05:57 |
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First Decision by Editorial Office Director |
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2025-12-09 10:06 |
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Return for Revision |
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2025-12-09 10:06 |
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Revised |
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2025-12-15 06:44 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-02 02:59 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-03 02:12 |
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Articles in Press |
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2026-02-03 02:12 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-14 03:29 |
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Publish the Manuscript Online |
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2026-04-17 07:17 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Correspondence |
| Article Title |
Letter to the Editor: Unveiling a novel vitamin D receptor signaling pathway for allyl isothiocyanate against metabolic dysfunction-associated steatotic liver disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ming Liu, Chun Guo, Peng Zhang and Shang-Ming Liu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Peng Zhang, Medical Basic Experiment Teaching Center, School of Basic Medical Sciences, Shandong University, No. 44, Wenhua Xi Road, Lixia District, Jinan 250012, Shandong Province, China. zhangpeng1990@sdu.edu.cn |
| Key Words |
Allyl isothiocyanate; Metabolic dysfunction-associated steatotic liver disease; Vitamin D receptor; Lipid metabolism; Fatty acid β-oxidation; Insulin resistance |
| Core Tip |
Gao et al identify a novel pathway for allyl isothiocyanate-mediated improvement of metabolic dysfunction-associated steatotic liver disease, involving the activation of the vitamin D receptor (VDR) signaling pathway in hepatocytes. We further propose that transient receptor potential ankyrin 1-mediated calcium signaling may act upstream of VDR activation, offering an alternative mechanistic insight. Future work needs to give priority to validating causality, particularly through VDR-knockout models and well-characterized in vivo models, such as high-fat diet or genetic metabolic dysfunction-associated steatotic liver disease models. This would allow researchers to evaluate the impact of allyl isothiocyanate, which is crucial for therapeutic translation. |
| Publish Date |
2026-04-17 07:17 |
| Citation |
Liu M, Guo C, Zhang P, Liu SM. Letter to the Editor: Unveiling a novel vitamin D receptor signaling pathway for allyl isothiocyanate against metabolic dysfunction-associated steatotic liver disease. World J Gastroenterol 2026; 32(16): 116951 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i16/116951.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i16.116951 |
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