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6/15/2026 8:38:29 AM | Browse: 1 | Download: 0
Publication Name World Journal of Nephrology
Manuscript ID 116961
Country Egypt
Received
2025-11-25 04:04
Peer-Review Started
2025-11-25 04:04
First Decision by Editorial Office Director
2025-12-09 09:27
Return for Revision
2025-12-09 09:27
Revised
2025-12-20 23:23
Publication Fee Transferred
Second Decision by Editor
2026-02-02 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-02 06:09
Articles in Press
2026-02-02 06:09
Edit the Manuscript by Language Editor
2026-02-08 00:14
Typeset the Manuscript
2026-05-07 10:44
Publish the Manuscript Online
2026-06-15 08:38
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Urology & Nephrology
Manuscript Type Prospective Study
Article Title Early detection of contrast-associated acute kidney injury after coronary angiography: A predictive value of osteopontin
Manuscript Source Invited Manuscript
All Author List Nashwa M Azoz, Noura G Nasr, Mohamad A Sobh, Ahmed Abdel-Galeel, Randa A Elzohne, Rabea A Gadelkareem and Alaa O Ahmed
ORCID
Author(s) ORCID Number
Nashwa M Azoz http://orcid.org/0000-0002-8455-1920
Noura G Nasr http://orcid.org/0009-0006-6465-0194
Mohamad A Sobh http://orcid.org/0009-0000-9127-3861
Ahmed Abdel-Galeel http://orcid.org/0000-0003-3712-5424
Randa A Elzohne http://orcid.org/0009-0001-4478-050X
Rabea A Gadelkareem http://orcid.org/0000-0003-4403-2859
Alaa O Ahmed http://orcid.org/0009-0007-6015-772X
Funding Agency and Grant Number
Funding Agency Grant Number
the Grants Office, Faculty of Medicine, Assiut University (Egypt) 2022-09-25-001
Corresponding Author Rabea A Gadelkareem, Department of Urology, Assiut Urology and Nephrology Hospital, Faculty of Medicine, Assiut University, Elgamaa Street, Assiut 71711, Egypt. rabeagad@aun.edu.eg
Key Words Acute kidney injury; Contrast; Contrast-associated acute kidney injury; Coronary angiography; Nephropathy; Osteopontin
Core Tip Serum osteopontin (OPN) is a strong and independent biomarker for predicting contrast-associated acute kidney injury after percutaneous coronary intervention. Its combination with the Mehran risk score offers the highest diagnostic accuracy. The current study presents novel evidence that OPN levels, measured before and after percutaneous coronary intervention, are significantly elevated in patients with contrast-associated acute kidney injury, identifying OPN as one of the most robust and independent predictors (alongside the Mehran score and contrast volume). Integrating OPN with the Mehran score yielded a diagnostic accuracy of 88%, suggesting that OPN should be incorporated into risk stratification strategies for timely preventive interventions.
Publish Date 2026-06-15 08:38
Citation

Azoz NM, Nasr NG, Sobh MA, Abdel-Galeel A, Elzohne RA, Gadelkareem RA, Ahmed AO. Early detection of contrast-associated acute kidney injury after coronary angiography: A predictive value of osteopontin. World J Nephrol 2026; 15(2): 116961

URL https://www.wjgnet.com/2220-6124/full/v15/i2/116961.htm
DOI https://doi.org/10.5527/wjn.v15.i2.116961
Full Article (PDF) WJN-15-116961-with-cover.pdf
CONSORT 2010 Statement 116961-CONSORT-2010-statement.pdf
Manuscript File 116961_Auto_Edited_080416.docx
Answering Reviewers 116961-answering-reviewers.pdf
Audio Core Tip 116961-audio.mp3
Biostatistics Review Certificate 116961-biostatistics-statement.pdf
Clinical Trial Registration Statement 116961-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 116961-conflict-of-interest-statement.pdf
Copyright License Agreement 116961-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 116961-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 116961-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 116961-non-native-speakers.pdf
Peer-review Report 116961-peer-reviews.pdf
Scientific Misconduct Check 116961-scientific-misconduct-check.png
Scientific Editor Work List 116961-scientific-editor-work-list.pdf
CrossCheck Report 116961-crosscheck-report.pdf