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3/15/2026 6:19:13 AM | Browse: 6 | Download: 25
Publication Name World Journal of Experimental Medicine
Manuscript ID 117024
Country India
Received
2025-11-27 01:06
Peer-Review Started
2025-11-27 07:31
First Decision by Editorial Office Director
2025-12-09 08:50
Return for Revision
2025-12-09 08:50
Revised
2025-12-23 10:40
Publication Fee Transferred
Second Decision by Editor
2026-02-12 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-12 07:35
Articles in Press
2026-02-12 07:35
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-27 07:06
Publish the Manuscript Online
2026-03-15 06:19
ISSN 2220-315x (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biochemical Research Methods
Manuscript Type Review
Article Title Very low-density lipoprotein and the human health
Manuscript Source Invited Manuscript
All Author List Alok Bharadwaj, Manas Taneja, Sneha Dubey and Aditya Saxena
ORCID
Author(s) ORCID Number
Alok Bharadwaj http://orcid.org/0000-0002-7383-188X
Manas Taneja http://orcid.org/0009-0005-3697-3714
Sneha Dubey http://orcid.org/0009-0005-4689-6388
Aditya Saxena http://orcid.org/0000-0002-0520-6409
Funding Agency and Grant Number
Corresponding Author Alok Bharadwaj, Associate Professor, PhD, Department of Biotechnology, GLA University, 17 Kilometre Mile Stone, Mathura-Delhi Highway NH-1, Mathura 281406, Uttar Pradesh, India. alok.bhardwaj@gla.ac.in
Key Words Very low-density lipoprotein metabolism; Physiological health; Pathological function; Lipids; Cholesterol; High blood pressure-based cardiovascular disease
Core Tip The liver secretes very low-density lipoprotein (VLDL), implicated in diseases such as atherosclerosis, metabolic-associated fatty liver disease, cognitive impairment, metabolic syndrome, autoimmune disorders, breast cancer, and head and neck cancer. VLDL contributes to atrial myopathy in the preclinical stage of atrial fibrillation and exhibits cytotoxic effects in myocardial infarction, though the mechanism remains unclear. Endocrine disorders can alter VLDL levels, and VLDL has been shown to increase aldosterone production. Its pathogenic role extends to extrahepatic release, neurological disorders, sleep disturbances, and various malignancies. Understanding VLDL regulation and metabolism, rather than just its levels, may clarify its role in disease and guide targeted therapeutic strategies.
Publish Date 2026-03-15 06:19
Citation

Bharadwaj A, Taneja M, Dubey S, Saxena A. Very low-density lipoprotein and the human health. World J Exp Med 2026; 16(1): 117024

URL https://www.wjgnet.com/2220-315x/full/v16/i1/117024.htm
DOI https://dx.doi.org/10.5493/wjem.v16.i1.117024
Full Article (PDF) WJEM-16-117024-with-cover.pdf
Manuscript File 117024_Auto_Edited_075421.docx
Answering Reviewers 117024-answering-reviewers.pdf
Audio Core Tip 117024-audio.mp3
Conflict-of-Interest Disclosure Form 117024-conflict-of-interest-statement.pdf
Copyright License Agreement 117024-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 117024-non-native-speakers.pdf
Peer-review Report 117024-peer-reviews.pdf
Scientific Misconduct Check 117024-scientific-misconduct-check.png
Scientific Editor Work List 117024-scientific-editor-work-list.pdf
CrossCheck Report 117024-crosscheck-report.pdf