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Articles Published Processes
3/26/2026 9:22:56 AM | Browse: 7 | Download: 55
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Received |
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2025-11-27 01:08 |
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Peer-Review Started |
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2025-11-27 01:08 |
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First Decision by Editorial Office Director |
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2025-12-16 09:12 |
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Return for Revision |
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2025-12-16 09:12 |
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Revised |
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2025-12-17 03:06 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-22 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-22 06:09 |
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Articles in Press |
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2026-01-22 06:09 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-16 11:10 |
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Publish the Manuscript Online |
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2026-03-26 09:22 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Multimarker model for non-invasive assessment of variceal bleeding in chronic hepatitis C cirrhotic patients
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Amira Ahmed Abdelrahman Othman, Lamiaa Elsharkawy, Mohamed W Saleh, Mohamed Medhat Mohamed and Fatma M Attia Elsayed |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Amira Ahmed Abdelrahman Othman, Lecturer, MD, PhD, Principal Investigator, Department of Internal Medicine, Suez University, Cairo-Suez Road, Suez 43511, Suez, Egypt. amira.othman@med.suezuni.edu.eg |
| Key Words |
Thyroid dysfunction; Hepatitis C; Cirrhosis; Portal hypertension; International normalized ratio; Platelet count; Portal hemodynamics |
| Core Tip |
This study validates a novel, non-invasive multimarker approach for identifying chronic hepatitis C cirrhotic patients at high risk for variceal bleeding. We identified a core panel of independent predictors: Low free triiodothyronine levels, low platelet count, and high international normalized ratio. A composite Variceal Risk Score integrating these with portal vein diameter demonstrated outstanding accuracy (area under the curve = 0.94). This strategy can efficiently triage patients for endoscopic screening, potentially reducing procedural burden in resource-limited settings. |
| Publish Date |
2026-03-26 09:22 |
| Citation |
Othman AAA, Elsharkawy L, Saleh MW, Mohamed MM, Elsayed FMA. Multimarker model for non-invasive assessment of variceal bleeding in chronic hepatitis C cirrhotic patients. World J Hepatol 2026; 18(3): 117040 |
| URL |
https://www.wjgnet.com/1948-5182/full/v18/i3/117040.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v18.i3.117040 |
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