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Articles Published Processes
5/20/2026 8:22:30 AM | Browse: 1 | Download: 0
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Received |
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2025-12-01 00:56 |
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Peer-Review Started |
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2025-12-01 00:56 |
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First Decision by Editorial Office Director |
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2025-12-16 10:01 |
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Return for Revision |
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2025-12-16 10:01 |
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Revised |
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2025-12-30 04:07 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-03-02 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-02 10:33 |
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Articles in Press |
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2026-03-02 10:33 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-13 00:37 |
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Publish the Manuscript Online |
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2026-05-20 08:22 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Gastric microenvironment and gastric cancer: Interplay of acid, microbiota, and inflammation
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Hao-Cheng Zheng, Ting Zhou, Lei Sun and Xia Ding |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China (General Program) |
82374292 |
| Innovation Team and Talents Cultivation Program of the National Administration of Traditional Chinese Medicine |
ZYYCXTD-C-202401 |
| Noncommunicable Chronic Diseases-National Science and Technology Major Project |
2025ZD0545100 |
| the Plans for Major Provincial Science & Technology Projects of Anhui Province |
202303a07020003 |
| the Fundamental Research Funds for the Central Universities of Beijing University of Chinese Medicine |
2025-JYB-JBGS-025 |
| Graduate Students’ Independent Scientific Research Project, Beijing University of Chinese Medicine |
ZJKT2025004 |
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| Corresponding Author |
Xia Ding, MD, PhD, Professor, School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, No. 11 North Third Ring East Road, Chaoyang District, Beijing 102488, China. dingx@bucm.edu.cn |
| Key Words |
Gastric microenvironment; Gastric acid; Parietal cells; Helicobacter pylori; Gastric microbiota |
| Core Tip |
Gastric microenvironment is shaped by gastric acid secretion, microbiota composition, and mucosal inflammation, which collectively drive the progression from gastritis to metaplasia and gastric cancer. Their bidirectional interactions create a self-reinforcing cycle of hypochlorhydria, microbial dysbiosis, and chronic inflammation. This comprehensive review provides an integrated perspective on these processes, offering updated insights into pathogenic mechanisms, risk stratification, and potential preventive or therapeutic strategies. |
| Publish Date |
2026-05-20 08:22 |
| Citation |
Zheng HC, Zhou T, Sun L, Ding X. Gastric microenvironment and gastric cancer: Interplay of acid, microbiota, and inflammation. World J Gastroenterol 2026; 32(20): 117044 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i20/117044.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i20.117044 |
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