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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 117057
Country China
Received
2025-11-27 02:20
Peer-Review Started
2025-11-27 02:20
First Decision by Editorial Office Director
2025-12-09 10:06
Return for Revision
2025-12-10 12:41
Revised
2025-12-23 14:58
Publication Fee Transferred
2025-12-26 07:22
Second Decision by Editor
2026-01-26 02:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-26 08:46
Articles in Press
2026-01-26 08:46
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-24 09:31
Publish the Manuscript Online
2026-06-09 09:23
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Cohort Study
Article Title Adjuvant programmed death-1 inhibition combined with chemotherapy in resected pancreatic cancer: A real-world cohort study
Manuscript Source Unsolicited Manuscript
All Author List Tang Cao, Xiang-Liang Deng, Jin Xiao, Xiao-Hong Tao, Xue-Lian Xiang, Man Qiu and Xiao-Yan Liang
ORCID
Author(s) ORCID Number
Tang Cao http://orcid.org/0009-0008-4115-1872
Xiao-Yan Liang http://orcid.org/0009-0009-2783-851X
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82273125
Natural Science Foundation of Chongqing CSTB2022NSCQ-MSX0803
High-level Medical Reserved Personnel Training Project of Chongqing 2023GDRC009
Corresponding Author Xiao-Yan Liang, Department of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing 400016, China. lxyan@hospital.cqmu.edu.cn
Key Words Pancreatic ductal adenocarcinoma; Programmed death-1 inhibitor; Adjuvant therapy; Recurrencefree survival; Immunotherapy; Real world study
Core Tip This real-world retrospective cohort study investigated the potential role of programmed death-1 (PD-1) inhibitor-based adjuvant therapy in patients with resected pancreatic ductal adenocarcinoma (PDAC), a population characterized by high recurrence risk after surgery. By comparing adjuvant chemotherapy alone with chemotherapy combined with PD-1 inhibition, this study demonstrated improved recurrence-free outcomes without an increase in severe treatment-related adverse events. These findings provide real-world clinical evidence supporting the feasibility of incorporating immunotherapy into postoperative adjuvant treatment strategies for resected PDAC.
Publish Date 2026-06-09 09:23
Citation

Cao T, Deng XL, Xiao J, Tao XH, Xiang XL, Qiu M, Liang XY. Adjuvant programmed death-1 inhibition combined with chemotherapy in resected pancreatic cancer: A real-world cohort study. World J Gastrointest Oncol 2026; 18(6): 117057

URL https://www.wjgnet.com/1948-5204/full/v18/i6/117057.htm
DOI https://doi.org/10.4251/wjgo.v18.i6.117057
Full Article (PDF) WJGO-18-117057-with-cover.pdf
STROBE Statement 117057-STROBE-statement.pdf
Manuscript File 117057_Auto_Edited_124711-YJP.docx
Answering Reviewers 117057-answering-reviewers.pdf
Audio Core Tip 117057-audio.m4a
Biostatistics Review Certificate 117057-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 117057-conflict-of-interest-statement.pdf
Copyright License Agreement 117057-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 117057-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 117057-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 117057-non-native-speakers.pdf
Supplementary Material 117057-supplementary-material.pdf
Peer-review Report 117057-peer-reviews.pdf
Scientific Misconduct Check 117057-scientific-misconduct-check.png
Scientific Editor Work List 117057-scientific-editor-work-list.pdf
CrossCheck Report 117057-crosscheck-report.pdf