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4/14/2026 8:58:01 AM | Browse: 2 | Download: 21
Publication Name World Journal of Diabetes
Manuscript ID 117063
Country China
Received
2025-11-28 01:15
Peer-Review Started
2025-12-01 09:05
First Decision by Editorial Office Director
2025-12-30 05:58
Return for Revision
2025-12-30 05:58
Revised
2026-01-08 21:57
Publication Fee Transferred
2026-01-13 11:07
Second Decision by Editor
2026-02-04 02:56
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-11 06:25
Articles in Press
2026-02-11 06:25
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-01 06:03
Publish the Manuscript Online
2026-04-14 08:58
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Observational Study
Article Title Product of C-reactive protein and fasting C-peptide indicates cardiovascular risk in type 2 diabetes: A real-world study
Manuscript Source Unsolicited Manuscript
All Author List Ya-Wen Zhang, Man-Rong Xu, Meng-Han Li and Lian-Xi Li
ORCID
Author(s) ORCID Number
Ya-Wen Zhang http://orcid.org/0000-0002-7840-0480
Man-Rong Xu http://orcid.org/0000-0002-0519-1593
Meng-Han Li http://orcid.org/0009-0002-6981-6078
Lian-Xi Li http://orcid.org/0000-0001-6073-4901
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81770813
National Natural Science Foundation of China 82070866
the National Key Research and Development Plan 2018YFC1314905
Corresponding Author Lian-Xi Li, MD, PhD, Department of Endocrinology and Metabolism, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Key Clinical Center for Metabolic Disease, 600 Yishan Road, Shanghai 200233, China. lilx@sjtu.edu.cn
Key Words Type 2 diabetes mellitus; C-reactive protein; C-peptide; Cardiovascular diseases; Risk factor; Real-world study
Core Tip This study introduces the product of C-reactive protein and fasting C-peptide as a novel composite indicator. It better reflects the combined effects of inflammation and insulin resistance and shows more stable associations with cardiovascular and cerebrovascular events than either component alone in patients with type 2 diabetes mellitus, supporting its potential value as a composite marker reflecting the overall cardiovascular risk burden.
Publish Date 2026-04-14 08:58
Citation

Zhang YW, Xu MR, Li MH, Li LX. Product of C-reactive protein and fasting C-peptide indicates cardiovascular risk in type 2 diabetes: A real-world study. World J Diabetes 2026; 17(4): 117063

URL https://www.wjgnet.com/1948-9358/full/v17/i4/117063.htm
DOI https://dx.doi.org/10.4239/wjd.v17.i4.117063
Full Article (PDF) WJD-17-117063-with-cover.pdf
STROBE Statement 117063-STROBE-statement.pdf
Manuscript File 117063_Auto_Edited_030832.docx
Answering Reviewers 117063-answering-reviewers.pdf
Audio Core Tip 117063-audio.m4a
Biostatistics Review Certificate 117063-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 117063-conflict-of-interest-statement.pdf
Copyright License Agreement 117063-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 117063-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 117063-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 117063-non-native-speakers.pdf
Supplementary Material 117063-supplementary-material.pdf
Peer-review Report 117063-peer-reviews.pdf
Journal Editor-in-Chief Review Report 117063-journal-editor-in-chief.pdf
Scientific Misconduct Check 117063-scientific-misconduct-check.docx
Scientific Editor Work List 117063-scientific-editor-work-list.pdf
CrossCheck Report 117063-crosscheck-report.pdf