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5/14/2026 9:17:09 AM | Browse: 5 | Download: 31
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 117085
Country China
Received
2025-12-02 09:39
Peer-Review Started
2025-12-02 09:39
First Decision by Editorial Office Director
2025-12-18 09:08
Return for Revision
2025-12-18 09:08
Revised
2025-12-29 11:56
Publication Fee Transferred
Second Decision by Editor
2026-02-06 02:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-06 11:02
Articles in Press
2026-02-06 11:02
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-28 00:15
Publish the Manuscript Online
2026-05-14 09:17
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Randomized Controlled Trial
Article Title Impact of sintilimab with first-line therapy on tumor marker response in advanced gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Hong-Liang Quan, Lin Xia, Yan Hu, Gui-Yuan Wang and Chao Wang
ORCID
Author(s) ORCID Number
Chao Wang http://orcid.org/0009-0006-0236-4889
Funding Agency and Grant Number
Funding Agency Grant Number
2024 Hefei BOE Hospital Institutional Research Project No. YJKT2024008
Anhui Provincial Higher Education Scientific Research Project (Natural Science Category) No. 2024AH050672
Corresponding Author Chao Wang, Chief Physician, Department of Oncology, The Fourth Affiliated Hospital of Anhui Medical University, No. 64 Chaohu North Road, Hefei 238000, Anhui Province, China. wangchao10107@163.com
Key Words Sintilimab; S-1 plus oxaliplatin regimen; Capecitabine plus oxaliplatin regimen; Advanced gastric cancer; Tumor markers; Carcinoembryonic antigen; Carbohydrate antigen 19-9; Carbohydrate antigen 72-4
Core Tip This study demonstrated that sintilimab plus S-1 plus oxaliplatin/xeloda plus oxaliplatin regimen therapy significantly enhanced the reduction in tumor markers and improved tumor marker response rates in patients with advanced gastric cancer. The early and profound decrease in these markers showed a significant positive correlation with objective tumor shrinkage, highlighting their potential as valuable dynamic indicators for evaluating the efficacy of this immunochemotherapy combination.
Publish Date 2026-05-14 09:17
Citation

Quan HL, Xia L, Hu Y, Wang GY, Wang C. Impact of sintilimab with first-line therapy on tumor marker response in advanced gastric cancer. World J Gastrointest Oncol 2026; 18(5): 117085

URL https://www.wjgnet.com/1948-5204/full/v18/i5/117085.htm
DOI https://dx.doi.org/10.4251/wjgo.v18.i5.117085
Full Article (PDF) WJGO-18-117085-with-cover.pdf
CONSORT 2010 Statement 117085-CONSORT-2010-statement.pdf
Manuscript File 117085_Auto_Edited_024129.docx
Answering Reviewers 117085-answering-reviewers.pdf
Audio Core Tip 117085-audio.m4a
Biostatistics Review Certificate 117085-biostatistics-statement.pdf
Clinical Trial Registration Statement 117085-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 117085-conflict-of-interest-statement.pdf
Copyright License Agreement 117085-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 117085-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 117085-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 117085-non-native-speakers.pdf
Peer-review Report 117085-peer-reviews.pdf
Scientific Misconduct Check 117085-scientific-misconduct-check.png
Scientific Editor Work List 117085-scientific-editor-work-list.pdf
CrossCheck Report 117085-crosscheck-report.pdf