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Articles Published Processes
3/15/2026 6:19:13 AM | Browse: 7 | Download: 35
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Received |
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2025-12-01 00:48 |
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Peer-Review Started |
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2025-12-01 00:48 |
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First Decision by Editorial Office Director |
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2025-12-17 09:31 |
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Return for Revision |
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2025-12-17 09:31 |
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Revised |
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2025-12-22 06:37 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-03 02:33 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-03 08:42 |
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Articles in Press |
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2026-02-03 08:42 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-02-27 07:08 |
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Publish the Manuscript Online |
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2026-03-15 06:19 |
| ISSN |
2220-315x (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Dentistry, Oral Surgery & Medicine |
| Manuscript Type |
Randomized Clinical Trial |
| Article Title |
Indocyanine green doped with chitosan nanoparticles based antimicrobial photodynamic therapy in periodontitis patients: A randomized clinical trial
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Subash Chandra Raj, Sudip Sen, Debajani Baral, Devapratim Mohanty, Shaheda Tabassum, Swoyangprava Sil and Mrutyunjaya Sahu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Subash Chandra Raj, Full Professor, Head, Department of Periodontics, SCB Dental College and Hospital, Mangalabag Road, cuttack 753003, Odisha, India. drsubash007@gmail.com |
| Key Words |
Periodontitis; Scaling and root planing; Photodynamic therapy; Nanoparticles; Chitosan; Indocyanine green |
| Core Tip |
This trial assesses the adjunctive use of indocyanine green-doped chitosan nanoparticles (CNPs-ICG) in antimicrobial photodynamic therapy (aPDT) with scaling and root planing (SRP) for periodontitis management. Conducted at SCB Dental College and Hospital, Cuttack, on 30 patients, the trial demonstrated significantly superior clinical and microbiological outcomes-particularly in improvement in probing depth, gain in clinical attachment level, and bacterial elimination-in comparison to conventional SRP alone. CNPs-ICG enhanced biofilm targeting and treatment precision through improved photosensitizer delivery. The findings highlight aPDT with CNPs-ICG as an effective, non-surgical, and minimally invasive alternative for patients unsuitable for periodontal surgery. |
| Publish Date |
2026-03-15 06:19 |
| Citation |
Raj SC, Sen S, Baral D, Mohanty D, Tabassum S, Sil S, Sahu M. Indocyanine green doped with chitosan nanoparticles based antimicrobial photodynamic therapy in periodontitis patients: A randomized clinical trial. World J Exp Med 2026; 16(1): 117125 |
| URL |
https://www.wjgnet.com/2220-315x/full/v16/i1/117125.htm |
| DOI |
https://dx.doi.org/10.5493/wjem.v16.i1.117125 |
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