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Articles Published Processes
8/5/2026 7:53:12 AM | Browse: 1 | Download: 0
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Received |
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2026-01-02 13:00 |
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Peer-Review Started |
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2026-01-05 08:26 |
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First Decision by Editorial Office Director |
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2026-01-21 06:56 |
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Return for Revision |
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2026-01-21 06:56 |
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Revised |
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2026-02-10 15:40 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-03-02 02:48 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-02 07:02 |
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Articles in Press |
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2026-03-02 07:02 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-22 08:39 |
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Publish the Manuscript Online |
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2026-08-05 07:53 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Correspondence |
| Article Title |
Serum bile acid profiling for diabetic gastrointestinal neuropathy: Promise and pitfalls
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yu-Hong Zhan and Xian-Feng Zhang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Zhejiang Provincial Medical and Health Science and Technology Program Project |
2025KY1092 |
| Zhejiang Provincial Traditional Chinese Medicine Science and Technology Project |
2025ZL454 |
| Construction Fund of Key Medical Disciplines of Hangzhou (Clinical Research and Evaluation) |
2025HZGF04 |
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| Corresponding Author |
Xian-Feng Zhang, Department of Endocrinology & Metabolism, Affiliated Hangzhou First People’s Hospital, Westlake University School of Medicine, No. 261 Huansha Road, Hangzhou 310006, Zhejiang Province, China. zxf2541@zju.edu.cn |
| Key Words |
TGR5 receptor; Biomarker; Taurolithocholic acid; Bile acids; Diabetic gastroparesis; Diabetic autonomic neuropathy; Type 2 diabetes mellitus |
| Core Tip |
This article critically appraises a novel study linking altered bile acid profiles, specifically taurolithocholic acid, to diabetic gastrointestinal autonomic neuropathy (DGAN). While the findings are biologically plausible and suggest a promising diagnostic model, significant limitations exist. The small sample size, cross-sectional design, and confounding by disease severity and treatment necessitate caution. The results are hypothesis-generating and underscore the need for large-scale validation before this potential biomarker can be considered for clinical risk stratification of DGAN. |
| Publish Date |
2026-08-05 07:53 |
| Citation |
Zhan YH, Zhang XF. Serum bile acid profiling for diabetic gastrointestinal neuropathy: Promise and pitfalls. World J Diabetes 2026; 17(8): 117130
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| URL |
https://www.wjgnet.com/1948-9358/full/v17/i8/117130.htm |
| DOI |
https://doi.org/10.4239/wjd.117130 |
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