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Publication Name World Journal of Clinical Cases
Manuscript ID 117165
Country Egypt
Received
2025-12-01 02:11
Peer-Review Started
2025-12-01 02:11
First Decision by Editorial Office Director
2025-12-12 08:01
Return for Revision
2025-12-12 08:01
Revised
2025-12-15 04:47
Publication Fee Transferred
Second Decision by Editor
2026-01-06 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-06 06:25
Articles in Press
2026-01-06 06:25
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-19 01:01
Publish the Manuscript Online
2026-01-22 07:08
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Case Report
Article Title Cachexia as an unusual presentation of familial mediterranean fever: A case report
Manuscript Source Invited Manuscript
All Author List Ahmed Mostafa Sira, Samar Ahmed Shoeir and Mostafa Mohamed Sira
ORCID
Author(s) ORCID Number
Ahmed Mostafa Sira http://orcid.org/0009-0006-0816-6779
Samar Ahmed Shoeir http://orcid.org/0009-0006-9919-0749
Mostafa Mohamed Sira http://orcid.org/0000-0002-3272-0497
Funding Agency and Grant Number
Corresponding Author Mostafa Mohamed Sira, MD, Professor, Department of Pediatric Hepatology, Gastroenterology, and Nutrition, National Liver Institute, Menoufia University, Gamal Abdel Nasser Street, Shebin El-Koom 32511, Menoufia, Egypt. msira@liver.menofia.edu.eg
Key Words Atypical presentation; Cachexia; Familial mediterranean fever; Myalgia; Case report
Core Tip Familial mediterranean fever is classically defined by recurrent episodes of spontaneous serositis with fever, but some children present with significant inflammation despite lacking these typical features. This case describes a 9-year-old girl with cachexia, debilitating myalgia, and recurrent fever, an atypical phenotype that created substantial diagnostic difficulty, especially with negative MEditerranean FeVer gene mutation testing. Her course underscores how familial mediterranean fever may manifest beyond standard criteria and why clinicians must look beyond genetic results. A detailed history and careful clinical assessment were ultimately key to recognizing the disease.
Publish Date 2026-01-22 07:08
Citation

Sira AM, Shoeir SA, Sira MM. Cachexia as an unusual presentation of familial mediterranean fever: A case report. World J Clin Cases 2026; 14(3): 117165

URL https://www.wjgnet.com/2307-8960/full/v14/i3/117165.htm
DOI https://dx.doi.org/10.12998/wjcc.v14.i3.117165
Full Article (PDF) WJCC-14-117165-with-cover.pdf
CARE Checklist–2016 117165-CARE-Checklist-2016.pdf
Manuscript File 117165_Auto_Edited_091714.docx
Answering Reviewers 117165-answering-reviewers.pdf
Audio Core Tip 117165-audio.mp3
Conflict-of-Interest Disclosure Form 117165-conflict-of-interest-statement.pdf
Copyright License Agreement 117165-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 117165-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 117165-non-native-speakers.pdf
Peer-review Report 117165-peer-reviews.pdf
Scientific Misconduct Check 117165-scientific-misconduct-check.png
Scientific Editor Work List 117165-scientific-editor-work-list.pdf
CrossCheck Report 117165-crosscheck-report.pdf