3/16/2026 9:13:12 AM | Browse: 4 | Download: 0
| Publication Name | World Journal of Clinical Cases |
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| Manuscript ID | 117167 |
| Country | Greece |
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| ISSN | 2307-8960 (online) |
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| Open Access | This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright | ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
| Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
| Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website | http://www.wjgnet.com |
| Category | Neurosciences |
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| Manuscript Type | Retrospective Study |
| Article Title | Correlation between esmolol usage in the acute phase of ischemic stroke and outcomes of patients undergoing intravenous thrombolysis |
| Manuscript Source | Invited Manuscript |
| All Author List | Panagiotis Papamichalis, Sophia K Papathanasiou, Apostolia Lemonia Skoura, Katerina G Oikonomou, Maria Xanthoudaki, Antonios Papadogoulas, Asimina Valsamaki, Dimitrios Plageras, Michail Papamichalis, Periklis Katsiafylloudis, Evangelia Papapostolou, Konstantinos Mantzarlis, Athanasios Koukoulis, Georgios D Koukoulis, Kyriaki Parisi, Grigorios Papapostolou, Vasileios Siokas, Efthimios Dardiotis and Achilleas Chovas |
| ORCID | |
| Funding Agency and Grant Number | |
| Corresponding Author | Panagiotis Papamichalis, MD, PhD, Intensive Care Unit, General Hospital of Larissa, 1 Tsakalof, Larissa 41221, Thessaly, Greece. ppapamih@med.uth.gr |
| Key Words | Thrombolysis; Alteplase; Esmolol; Arterial blood pressure; Complications; Mortality; Functional outcome |
| Core Tip | Various drugs, including esmolol, are used for managing elevated arterial blood pressure before intravenous thrombolysis for acute ischemic stroke. This study evaluated baseline characteristics and outcomes of 149 patients with a focus on esmolol-treated and esmolol-untreated groups. Sub-group analysis was performed to compare the outcomes between the esmolol-treated and esmolol-untreated subgroups among the following patient groups: Patients with atrial fibrillation (AF); patients without AF; patients with a history of hypertension; patients without a history of hypertension. Esmolol usage resulted in poor outcomes for the overall cohort, patients without AF, and patients without a history of hypertension but not for patients with AF and patients with a history of hypertension. |
| Publish Date | 2026-03-16 09:13 |
| Citation | Papamichalis P, Papathanasiou SK, Skoura AL, Oikonomou KG, Xanthoudaki M, Papadogoulas A, Valsamaki A, Plageras D, Papamichalis M, Katsiafylloudis P, Papapostolou E, Mantzarlis K, Koukoulis A, Koukoulis GD, Parisi K, Papapostolou G, Siokas V, Dardiotis E, Chovas A. Correlation between esmolol usage in the acute phase of ischemic stroke and outcomes of patients undergoing intravenous thrombolysis. World J Clin Cases 2026; 14(8): 117167 |
| URL | https://www.wjgnet.com/2307-8960/full/v14/i8/117167.htm |
| DOI | https://dx.doi.org/10.12998/wjcc.v14.i8.117167 |
| Full Article (PDF) | WJCC-14-117167-with-cover.pdf |
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| Manuscript File | 117167_Auto_Edited_015656.docx |
| Answering Reviewers | 117167-answering-reviewers.pdf |
| Audio Core Tip | 117167-audio.mp3 |
| Biostatistics Review Certificate | 117167-biostatistics-statement.pdf |
| Conflict-of-Interest Disclosure Form | 117167-conflict-of-interest-statement.pdf |
| Copyright License Agreement | 117167-copyright-assignment.pdf |
| Signed Informed Consent Form(s) or Document(s) | 117167-informed-consent-statement.pdf |
| Institutional Review Board Approval Form or Document | 117167-institutional-review-board-statement.pdf |
| Non-Native Speakers of English Editing Certificate | 117167-non-native-speakers.pdf |
| Peer-review Report | 117167-peer-reviews.pdf |
| Scientific Misconduct Check | 117167-scientific-misconduct-check.png |
| Scientific Editor Work List | 117167-scientific-editor-work-list.pdf |
| CrossCheck Report | 117167-crosscheck-report.pdf |