| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Hepatic resection in adolescent and young adult patients with hepatocellular carcinoma
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Junji Ueda, Nobuhiko Taniai, Masato Yoshioka, Akira Matsushita, Satoshi Mizutani, Yoichi Kawano, Tetsuya Shimizu, Tomohiro Kanda, Takahiro Murokawa, Hideyuki Takata, Hiroyasu Furuki, Yuto Aoki, Mampei Kawashima, Toshiyuki Irie, Takashi Ono, Takahiro Haruna, Daigo Yoshimori, Kazuhiko Endo, Akira Hamaguchi and Hiroshi Yoshida |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Junji Ueda, Associate Professor, Department of Gastroenterological Surgery, Nippon Medical School, -5-1, Sendagi Bunkyo-ku,, Bunkyo-ku 113-8603, Tokyo, Japan. junji0821@nms.ac.jp |
| Key Words |
Hepatocellular carcinoma; Hepatectomy; Adolescent and young adult; Lung metastasis; Overall survival |
| Core Tip |
This study evaluated outcomes of hepatic resection in adolescent and young adult (AYA; age 15-39 years) patients with hepatocellular carcinoma (HCC). Among 885 patients who underwent hepatectomy, 9 (1.0%) were classified as AYAs, with hepatitis B virus infection significantly more common and tumors larger in the AYA group than in non-AYA patients. However, tumor marker levels, vascular invasion, differentiation, overall survival, and recurrence-free survival did not differ between groups. Although rare, AYA HCC showed favorable surgical outcomes, highlighting the importance of early detection and timely hepatectomy. |
| Publish Date |
2026-05-20 08:53 |
| Citation |
Ueda J, Taniai N, Yoshioka M, Matsushita A, Mizutani S, Kawano Y, Shimizu T, Kanda T, Murokawa T, Takata H, Furuki H, Aoki Y, Kawashima M, Irie T, Ono T, Haruna T, Yoshimori D, Endo K, Hamaguchi A, Yoshida H. Hepatic resection in adolescent and young adult patients with hepatocellular carcinoma. World J Clin Oncol 2026; 17(5): 117168 |
| URL |
https://www.wjgnet.com/2218-4333/full/v17/i5/117168.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v17.i5.117168 |
