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7/14/2026 9:34:59 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 117181
Country India
Received
2025-12-01 03:13
Peer-Review Started
2025-12-03 09:15
First Decision by Editorial Office Director
2026-01-21 09:22
Return for Revision
2026-01-21 09:22
Revised
2026-02-01 08:39
Publication Fee Transferred
Second Decision by Editor
2026-03-05 02:48
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-05 12:35
Articles in Press
2026-03-05 12:35
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-26 06:26
Publish the Manuscript Online
2026-07-14 09:34
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Opinion Review
Article Title Do biomarkers matter? cardiovascular risk stratification in Asian metabolic dysfunction-associated steatotic liver disease in the era of fibrosis-centric assessment
Manuscript Source Invited Manuscript
All Author List Manjeet Kumar Goyal, Juniali Hatwal, Rupak Desai, Tanisha Sehgal and Akash Batta
ORCID
Author(s) ORCID Number
Manjeet Kumar Goyal http://orcid.org/0000-0002-5511-2099
Juniali Hatwal http://orcid.org/0000-0001-5433-0433
Rupak Desai http://orcid.org/0000-0002-5315-6426
Akash Batta http://orcid.org/0000-0002-7606-5826
Funding Agency and Grant Number
Corresponding Author Akash Batta, Department of Cardiology, Dayanand Medical College and Hospital, Tagore Nagar, Civil Lines, Ludhiana 141001, Punjab, India. akashbatta02@gmail.com
Key Words Cardiovascular diseases; Metabolic dysfunction-associated steatotic liver disease; Obesity; Uric acid; Endothelial dysfunction; High-density lipoprotein cholesterol, Framingham risk score
Core Tip Cardiovascular risk in Asian patients with metabolic dysfunction-associated steatotic liver disease is multifactorial and not adequately captured by single biomarkers. While metabolic indices reflect upstream metabolic stress, their prognostic value for cardiovascular events remains limited. Inflammatory markers are mechanistically relevant but confounded by their inclusion in disease definitions. In contrast, fibrosis-based scores, consistently associate with cardiovascular outcomes across Asian cohorts, likely reflecting cumulative metabolic injury. An integrated, multivariable approach combining metabolic, inflammatory, and fibrosis markers is more appropriate for cardiovascular risk stratification in this population.
Publish Date 2026-07-14 09:34
Citation

Goyal MK, Hatwal J, Desai R, Sehgal T, Batta A. Do biomarkers matter? cardiovascular risk stratification in Asian metabolic dysfunction-associated steatotic liver disease in the era of fibrosis-centric assessment. World J Gastroenterol 2026; 32(28): 117181

URL https://www.wjgnet.com/1007-9327/full/v32/i28/117181.htm
DOI https://doi.org/10.3748/wjg.117181
Full Article (PDF) WJG-32-117181-with-cover.pdf
Manuscript File 117181_Auto_Edited_062357.docx
Answering Reviewers 117181-answering-reviewers.pdf
Audio Core Tip 117181-audio.m4a
Conflict-of-Interest Disclosure Form 117181-conflict-of-interest-statement.pdf
Copyright License Agreement 117181-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 117181-non-native-speakers.pdf
Peer-review Report 117181-peer-reviews.pdf
Scientific Misconduct Check 117181-scientific-misconduct-check.png
Scientific Editor Work List 117181-scientific-editor-work-list.pdf
CrossCheck Report 117181-crosscheck-report.pdf