Publication Name	World Journal of Gastroenterology
Manuscript ID	11719
Country	China

Received	2014-06-01 11:09
Peer-Review Started	2014-06-02 22:39
To Make the First Decision	2014-07-21 13:33
Return for Revision	2014-07-28 14:42
Revised	2014-08-12 10:40
Second Decision	2014-09-05 16:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-09-05 17:17
Articles in Press	2014-09-05 17:27
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-09-23 04:30
Typeset the Manuscript	2015-01-30 15:23
Publish the Manuscript Online	2015-02-11 16:38

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Autobiography
Article Title	MicroRNA profiling of the intestine during hypothermic circulatory arrest in swine
Manuscript Source	Unsolicited Manuscript
All Author List	Wei-Bin Lin, Meng-Ya Liang, Guang-Xian Chen, Xiao Yang, Han Qin, Jian-Ping Yao, Kang-Ni Feng and Zhong-Kai Wu
Funding Agency and Grant Number	Funding Agency Grant Number National Basic Research Program of China（973 Program） 2010CB5295007 Pearl River Scholar Program 80000-3210003 Natural Science Fund of China 81370215
Corresponding Author	Zhong-kai Wu, MD, PhD, 2nd Department of Cardiac surgery, the First Affiliated Hospital of Sun Yat-Sen University, 58 Zhongshan II Road, Guangzhou 510080, Guangdong Province, China. wuzhk@mail.sysu.edu.cn
Key Words	Reperfusion injury; Cardiopulmonary bypass; Animal model; Barrier function; Randomized controlled trial; MicroRNA
Core Tip	Swine intestine was subjected to hypothermia, cardiopulmonary bypass and ischemia/reperfusion following hypothermic circulatory arrest (HCA). These factors caused barrier dysfunction, resulting in gastrointestinal complications. Histopathological and microRNA (miRNA) array analyses were used to investigate the effects of HCA on the gut barrier. HCA was found to disturb barrier function in the small intestine and influence the miRNA levels in swine. Our results contribute to the body of research examining gut barrier function following HCA in vivo.
Publish Date	2015-02-11 16:38
Citation	Lin WB, Liang MY, Chen GX, Yang X, Qin H, Yao JP, Feng KN, Wu ZK. MicroRNA profiling of the intestine during hypothermic circulatory arrest in swine. World J Gastroenterol 2015; 21(7): 2183-2190
URL	http://www.wjgnet.com/1007-9327/full/v21/i7/2183.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i7.2183

Full Article (PDF)	WJG-21-2183.pdf
Full Article (Word)	WJG-21-2183.doc
Manuscript File	11719-Review.doc
Answering Reviewers	11719-Answering reviewers.pdf
Copyright License Agreement	11719-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	11719-Language certificate.pdf
Peer-review Report	11719-Peer review(s).pdf
Scientific Misconduct Check	11719-CrossCheck.jpg
Scientific Editor Work List	11719-Scientific editor work list.pdf