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7/10/2026 10:11:17 AM | Browse: 1 | Download: 0
Publication Name World Journal of Methodology
Manuscript ID 117220
Country India
Received
2025-12-08 01:05
Peer-Review Started
2025-12-08 01:05
First Decision by Editorial Office Director
2025-12-12 09:08
Return for Revision
2025-12-12 09:08
Revised
2025-12-14 10:20
Publication Fee Transferred
Second Decision by Editor
2026-03-16 02:32
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-16 09:00
Articles in Press
2026-03-16 09:00
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-09 03:56
Publish the Manuscript Online
2026-07-10 10:11
ISSN 2222-0682 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Anesthesiology
Manuscript Type Randomized Controlled Trial
Article Title Comparison of propofol alone vs propofol-phenylephrine combination for intraoperative hemodynamic stability in glioma surgery
Manuscript Source Invited Manuscript
All Author List Rhea Thotungal, Ashutosh Kaushal, Amit Agrawal, Anuj Jain, Vaishali Waindeskar, Rudrashish Haldar and Pfokreni Lokho
ORCID
Author(s) ORCID Number
Rhea Thotungal http://orcid.org/0000-0002-4132-7398
Ashutosh Kaushal http://orcid.org/0000-0001-8552-7861
Amit Agrawal http://orcid.org/0000-0002-3287-5448
Anuj Jain http://orcid.org/0000-0003-0531-4343
Vaishali Waindeskar http://orcid.org/0000-0002-0556-7159
Rudrashish Haldar http://orcid.org/0000-0001-5875-5367
Pfokreni Lokho http://orcid.org/0009-0004-4281-8422
Funding Agency and Grant Number
Corresponding Author Ashutosh Kaushal, Additional Professor, DM, MD, Department of Anesthesiology and Critical Care, All India Institute of Medical Sciences, Saket Nagar, Bhopal 462026, Madhya Pradesh, India. drashutosh.kaushal@gmail.com
Key Words Propofol; Phenylephrine; Hemodynamic stability; Glioma surgery; Induction of anesthesia; Neuroanesthesia; Brain relaxation
Core Tip Propofol is widely preferred for the induction and maintenance in neuroanesthesia due to its neuroprotective properties. However, propofol frequently causes hypotension during the induction of anesthesia in neurosurgical patients, which may compromise cerebral perfusion. Therefore, combining phenylephrine with propofol significantly reduces induction-related hypotension, minimizes vasopressor requirement, and maintains stable intraoperative hemodynamics without affecting brain relaxation, offering a practical approach for neuroanesthesia in glioma surgery.
Publish Date 2026-07-10 10:11
Citation

Thotungal R, Kaushal A, Agrawal A, Jain A, Waindeskar V, Haldar R, Lokho P. Comparison of propofol alone vs propofol-phenylephrine combination for intraoperative hemodynamic stability in glioma surgery. World J Methodol 2026; 16(3): 117220

URL https://www.wjgnet.com/2222-0682/full/v16/i3/117220.htm
DOI https://doi.org/10.5662/wjm.117220
Full Article (PDF) WJM-16-117220-with-cover.pdf
CONSORT 2010 Statement 117220-CONSORT-2010-statement.pdf
Manuscript File 117220_Auto_Edited-0507-YJP.docx
Answering Reviewers 117220-answering-reviewers.pdf
Audio Core Tip 117220-audio.mp3
Biostatistics Review Certificate 117220-biostatistics-statement.pdf
Clinical Trial Registration Statement 117220-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 117220-conflict-of-interest-statement.pdf
Copyright License Agreement 117220-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 117220-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 117220-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 117220-non-native-speakers.pdf
Supplementary Material 117220-supplementary-material.pdf
Peer-review Report 117220-peer-reviews.pdf
Scientific Misconduct Check 117220-scientific-misconduct-check.png
Scientific Editor Work List 117220-scientific-editor-work-list.pdf
CrossCheck Report 117220-crosscheck-report.pdf