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Articles Published Processes
9/4/2026 5:57:43 AM | Browse: 1 | Download: 0
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Received |
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2025-12-02 00:57 |
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Peer-Review Started |
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2025-12-03 09:18 |
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First Decision by Editorial Office Director |
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2025-12-31 07:54 |
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Return for Revision |
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2025-12-31 07:54 |
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Revised |
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2026-01-14 03:34 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-04 02:48 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-04 12:06 |
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Articles in Press |
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2026-02-04 12:06 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-08-20 07:11 |
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Publish the Manuscript Online |
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2026-09-04 05:57 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Dermatology |
| Manuscript Type |
Editorial |
| Article Title |
Fractional carbon dioxide laser preconditioning potentiates adipose-derived mesenchymal stem cell exosomes for diabetic wound repair
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Chun-Yi Wu, Xie-Hua Xiao and Jian-Guo Feng |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Sichuan Science and Technology Program |
No. 2025ZNSFSC0744 |
| Health Commission of Sichuan Province Medical Science and Technology Program |
No. 24QNMP040 |
| Luzhou Science and Technology Program |
No. 2025RCX002 |
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| Corresponding Author |
Jian-Guo Feng, Associate Professor, PhD, Principal Investigator, Department of Anesthesiology, The Affiliated Hospital, Southwest Medical University, No.25th, Taiping Street, Luzhou, Luzhou 646000, Sichuan Province, China. fengjianguo@swmu.edu.cn |
| Key Words |
Angiogenesis.; Preconditioning; Fractional carbon dioxide laser; Exosomes; Mesenchymal stem cells; Diabetic wound healing |
| Core Tip |
This editorial highlight that fractional carbon dioxide (CO₂) laser pre-conditioning offers a novel, drug-free strategy to enhance the therapeutic quality of adipose-derived mesenchymal stem cell exosomes (Exos) for diabetic wound repair. We emphasize recent findings that this physical pre-conditioning strategy, utilizing clinically established and dose-tunable photothermal stimulation, enriches sphingosine-1-phosphate (S1P) cargo and activates endothelial S1P receptor 1/protein kinase B/hypoxia-inducible factor-1α signaling, thereby promoting improved angiogenesis and cytoprotection. This concept reframes fractional CO₂ lasers as a scalable, good manufacturing practice-compatible platform to “upgrade” Exos bioactivity for chronic diabetic wounds. |
| Publish Date |
2026-09-04 05:57 |
| Citation |
Wu CY, Xiao XH, Feng JG. Fractional carbon dioxide laser preconditioning potentiates adipose-derived mesenchymal stem cell exosomes for diabetic wound repair. World J Diabetes 2026; 17(9): 117228
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| URL |
https://www.wjgnet.com/1948-9358/full/v17/i9/117228.htm |
| DOI |
https://doi.org/10.4239/wjd.117228 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
