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Articles Published Processes
8/19/2026 1:55:09 AM | Browse: 0 | Download: 0
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Received |
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2025-12-02 02:22 |
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Peer-Review Started |
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2025-12-02 02:22 |
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First Decision by Editorial Office Director |
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2025-12-17 10:17 |
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Return for Revision |
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2025-12-17 10:17 |
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Revised |
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2026-03-05 01:47 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-07-27 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-07-27 03:15 |
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Articles in Press |
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2026-07-27 03:15 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-08-12 00:10 |
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Publish the Manuscript Online |
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2026-08-19 01:55 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Takeda Development Center Americas Inc 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Real-world inflammatory bowel disease-modification outcomes: A narrative review
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Neeraj Narula, Shashi Adsul and Walter Reinisch |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Walter Reinisch, MD, PhD, Department of Medicine III, Division for Gastroenterology and Hepatology, Medical University of Vienna, Währinger Gürtel 18-20, Vienna A-1090, Austria. walter.reinisch@meduniwien.ac.at |
| Key Words |
Crohn’s disease; Disease modification; Inflammatory bowel disease; Real-world evidence; Standard protocol items: Recommendations for interventional trials consensus; Ulcerative colitis |
| Core Tip |
The standard protocol items: Recommendations for interventional trials (SPIRIT) consensus has recommended disease-modification endpoints for use in clinical trials in patients with inflammatory bowel disease (IBD) to help determine if this approach can prevent disease progression. Before such studies are conducted, real-world evidence can be informative. This review of real-world studies utilizing the SPIRIT consensus endpoints identified considerable gaps in the use of these recommended disease-modification endpoints. Therefore, there remains a need to incorporate SPIRIT recommended disease-modification endpoints in prospective real-world studies in patients with IBD receiving advanced treatments. |
| Publish Date |
2026-08-19 01:55 |
| Citation |
Narula N, Adsul S, Reinisch W. Real-world inflammatory bowel disease-modification outcomes: A narrative review. World J Gastroenterol 2026; 32(34): 117240
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i34/117240.htm |
| DOI |
https://doi.org/10.3748/wjg.117240 |
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