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Articles Published Processes
5/25/2026 7:47:56 AM | Browse: 0 | Download: 0
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Received |
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2025-12-02 01:17 |
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Peer-Review Started |
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2025-12-02 01:17 |
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First Decision by Editorial Office Director |
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2025-12-26 10:25 |
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Return for Revision |
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2025-12-26 10:25 |
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Revised |
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2026-01-06 08:08 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-03-05 02:56 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-12 07:07 |
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Articles in Press |
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2026-03-12 07:07 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-13 00:26 |
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Publish the Manuscript Online |
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2026-05-25 07:47 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Hypoxic preconditioning restores the regenerative potential of aged adipose tissue derived mesenchymal stem cells
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Bushra Bashir, Mahmood S Choudhery and Ijaz Hussain |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mahmood S Choudhery, Department of Human Genetics and Molecular Biology, University of Health Sciences, Khayaban-e-Jamia, Lahore 54000, Punjab, Pakistan. ms20031@yahoo.com |
| Key Words |
Mesenchymal stem cells; Skin rejuvenation; Hypoxic preconditioning; Regenerative potential; Anti-aging therapy |
| Core Tip |
Mesenchymal stem cells (MSCs) exhibit age-related decline in their regenerative potential. Hypoxic preconditioning has been found to be an effective strategy to augment their regenerative potential. Aged adipose tissue derived MSCs subjected to hypoxic preconditioning (3% O2) for 48 hours exhibited enhanced proliferative potential, clonogenicity, differentiation capability, concurrent with reduced senescence. These findings suggest that hypoxic-preconditioning is a promising therapeutic option to enhance the regenerative potential of aged adipose tissue derived MSCs for autologous use. |
| Publish Date |
2026-05-25 07:47 |
| Citation |
Bashir B, Choudhery MS, Hussain I. Hypoxic preconditioning restores the regenerative potential of aged adipose tissue derived mesenchymal stem cells. World J Stem Cells 2026; 18(5): 117241 |
| URL |
https://www.wjgnet.com/1948-0210/full/v18/i5/117241.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v18.i5.117241 |
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