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7/9/2026 6:58:25 AM | Browse: 0 | Download: 0
Publication Name World Journal of Diabetes
Manuscript ID 117243
Country United States
Received
2025-12-03 00:53
Peer-Review Started
2025-12-03 08:45
First Decision by Editorial Office Director
2026-01-08 05:32
Return for Revision
2026-01-08 05:32
Revised
2026-01-16 04:05
Publication Fee Transferred
Second Decision by Editor
2026-01-27 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-27 06:51
Articles in Press
2026-01-27 06:51
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-29 13:50
Publish the Manuscript Online
2026-07-09 06:58
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Physiology
Manuscript Type Correspondence
Article Title Is the cellular attribution of liraglutide action in diabetic cardiomyopathy conclusive?
Manuscript Source Invited Manuscript
All Author List Ke Su, Pei-Yan Cao, Gan Chen and Ke Wu
ORCID
Author(s) ORCID Number
Ke Wu http://orcid.org/0000-0002-7195-9601
Funding Agency and Grant Number
Corresponding Author Ke Wu, Assistant Professor, MD, PhD, Investigator, Institute for Advanced Biomedical Research, Charles R. Drew University of Medicine and Science, 1731 E. 120th Street, Los Angeles, California 90059, United States. kewu@cdrewu.edu
Key Words Diabetic cardiomyopathy; Liraglutide; Glucagon-like peptide-1 receptor; Cardiomyocyte; Endothelial cells; Cell-type specificity
Core Tip The cellular targets mediating the cardioprotective effects of liraglutide in diabetic cardiomyopathy remain incompletely defined. While recent studies report beneficial cardiac phenotypes, the attribution of these effects to direct cardiomyocyte receptor signaling is not yet conclusively established. This correspondence highlights uncertainties related to cell-type specificity and potential non-myocyte contributions, and emphasizes the need for rigorous cell-type resolved validation. Clarifying the cellular basis of liraglutide action is critical for accurate mechanistic interpretation and future translational applications.
Publish Date 2026-07-09 06:58
Citation

Su K, Cao PY, Chen G, Wu K. Is the cellular attribution of liraglutide action in diabetic cardiomyopathy conclusive? World J Diabetes 2026; 17(7): 117243

URL https://www.wjgnet.com/1948-9358/full/v17/i7/117243.htm
DOI https://doi.org/10.4239/wjd.117243
Full Article (PDF) WJD-17-117243-with-cover.pdf
Manuscript File 117243_Auto_Edited_073917.docx
Answering Reviewers 117243-answering-reviewers.pdf
Audio Core Tip 117243-audio.mp3
Conflict-of-Interest Disclosure Form 117243-conflict-of-interest-statement.pdf
Copyright License Agreement 117243-copyright-assignment.pdf
Peer-review Report 117243-peer-reviews.pdf
Scientific Misconduct Check 117243-scientific-misconduct-check.png
Scientific Editor Work List 117243-scientific-editor-work-list.pdf
CrossCheck Report 117243-crosscheck-report.pdf