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Articles Published Processes
6/9/2026 9:23:57 AM | Browse: 0 | Download: 0
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Received |
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2025-12-03 01:55 |
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Peer-Review Started |
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2025-12-03 01:55 |
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First Decision by Editorial Office Director |
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2025-12-17 10:19 |
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Return for Revision |
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2025-12-17 13:17 |
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Revised |
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2025-12-19 13:20 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-09 02:47 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-09 07:38 |
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Articles in Press |
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2026-02-09 07:38 |
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Edit the Manuscript by Language Editor |
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2026-02-14 20:49 |
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Typeset the Manuscript |
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2026-04-24 09:38 |
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Publish the Manuscript Online |
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2026-06-09 09:23 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Storax oil and boron compounds trigger apoptosis and cell cycle arrest in gastric and colorectal cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Buket Er Urganci, Sacide Çakal, Cihangir Dogan, Sibel Göçmen, Selda Şimşek and Sevda Yılmaz |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Buket Er Urganci, Assistant Professor, Department of Medical Biology, Faculty of Medicine, Pamukkale University, Morphology Building, 3rd Floor, Denizli 20160, Türkiye. aber@pau.edu.tr |
| Key Words |
Gastric cancer; Colorectal cancer; Liquidambar oil; Boric acid; Borax; Apoptosis |
| Core Tip |
This study demonstrates that storax oil, boric acid, and borax exert strong anticancer activity in gastric and colorectal cancer cells. Treatments significantly induced apoptosis by upregulating p53, Bax, and caspases, while suppressing Bcl-2. Boron compounds enhanced cell cycle arrest via increased p21 and decreased CyclinD1 expression. Notably, combination treatments showed synergistic effects, producing greater apoptotic and anti-proliferative responses than individual agents. These findings highlight the potential of storax oil and boron derivatives as complementary therapeutic strategies, offering new insights into apoptosis and cell cycle regulation in gastrointestinal cancers. |
| Publish Date |
2026-06-09 09:23 |
| Citation |
Er Urganci B, Çakal S, Dogan C, Göçmen S, Şimşek S, Yılmaz S. Storax oil and boron compounds trigger apoptosis and cell cycle arrest in gastric and colorectal cancer. World J Gastrointest Oncol 2026; 18(6): 117252
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| URL |
https://www.wjgnet.com/1948-5204/full/v18/i6/117252.htm |
| DOI |
https://doi.org/10.4251/wjgo.v18.i6.117252 |
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