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Publication Name World Journal of Clinical Cases
Manuscript ID 117257
Country India
Received
2025-12-03 01:10
Peer-Review Started
2025-12-03 01:10
First Decision by Editorial Office Director
2025-12-09 08:37
Return for Revision
2025-12-09 08:37
Revised
2025-12-17 08:37
Publication Fee Transferred
Second Decision by Editor
2025-12-26 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-26 08:29
Articles in Press
2025-12-26 08:29
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-09 00:31
Publish the Manuscript Online
2026-01-22 07:08
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Ophthalmology
Manuscript Type Minireviews
Article Title Ocular health in outer space and beyond gravity: A minireview
Manuscript Source Invited Manuscript
All Author List Srishti Khullar, Arvind Kumar Morya, Sarita Aggarwal, Twinkle Gupta, Priyanka Priyanka and Rannusha Morya
ORCID
Author(s) ORCID Number
Srishti Khullar http://orcid.org/0000-0002-8079-9398
Arvind Kumar Morya http://orcid.org/0000-0003-0462-119X
Priyanka Priyanka http://orcid.org/0000-0001-6765-1746
Rannusha Morya http://orcid.org/0009-0002-1819-4846
Funding Agency and Grant Number
Corresponding Author Arvind Kumar Morya, Additional Professor, Consultant, Principal Investigator, Researcher, Senior Researcher, Department of Ophthalmology, All India Institute of Medical Sciences, Bibi Nagar, Hyderabad 508126, Telangāna, India. bulbul.morya@gmail.com
Key Words Spaceflight-associated neuro-ocular syndrome; Microgravity; Intracranial pressure; Ocular health; Astronaut physiology; Space medicine
Core Tip Vision is mission-critical in human spaceflight. Prolonged exposure to microgravity causes a distinct set of ocular changes known as spaceflight-associated neuro-ocular syndrome. These include optic disc edema, posterior globe flattening, choroidal folds, retinal nerve fiber layer thickening, and hyperopic refractive shifts. Evidence suggests spaceflight-associated neuro-ocular syndrome arises from cephalad fluid shifts, venous congestion, and altered cerebrospinal fluid dynamics rather than raised intracranial pressure alone. Advances in in-flight imaging and artificial intelligence are improving early detection, making ocular health central to safe space exploration and neuro-ophthalmic research.
Publish Date 2026-01-22 07:08
Citation

Khullar S, Morya AK, Aggarwal S, Gupta T, Priyanka P, Morya R. Ocular health in outer space and beyond gravity: A minireview. World J Clin Cases 2026; 14(3): 117257

URL https://www.wjgnet.com/2307-8960/full/v14/i3/117257.htm
DOI https://dx.doi.org/10.12998/wjcc.v14.i3.117257
Full Article (PDF) WJCC-14-117257-with-cover.pdf
Manuscript File 117257_Auto_Edited_035304.docx
Answering Reviewers 117257-answering-reviewers.pdf
Audio Core Tip 117257-audio.m4a
Conflict-of-Interest Disclosure Form 117257-conflict-of-interest-statement.pdf
Copyright License Agreement 117257-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 117257-non-native-speakers.pdf
Peer-review Report 117257-peer-reviews.pdf
Scientific Misconduct Check 117257-scientific-misconduct-check.png
Scientific Editor Work List 117257-scientific-editor-work-list.pdf
CrossCheck Report 117257-crosscheck-report.pdf