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Articles Published Processes
5/13/2026 8:18:28 AM | Browse: 1 | Download: 13
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Received |
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2025-12-03 01:19 |
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Peer-Review Started |
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2025-12-03 01:19 |
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First Decision by Editorial Office Director |
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2025-12-12 09:07 |
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Return for Revision |
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2025-12-12 09:07 |
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Revised |
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2025-12-13 18:09 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-24 02:45 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-24 09:33 |
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Articles in Press |
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2026-02-24 09:33 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-16 09:37 |
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Publish the Manuscript Online |
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2026-05-13 08:18 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Medical treatment of autism spectrum disorder in children: Current evidence, controversies, and clinical challenges
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yousif M Elbeltagi, Ahmed Osama Abd Rab El Rasool, Ahmed Mohammed Elkashlan and Mohammed Al-Beltagi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mohammed Al-Beltagi, Chairman, Consultant, Full Professor, MD, PhD, Senior Researcher, Department of Pediatrics, Faculty of Medicine, Tanta University, 1 Hassan Radwan Street, Tanta 31511, Algharbia, Egypt. mohamed.elbeltagi@med.tanta.edu.eg |
| Key Words |
Autism spectrum disorder; Pharmacological; Pediatric; Risperidone; Aripiprazole; Fecal microbiota transplantation; Microbiota-gut-brain axis; Precision medicine; Methylcobalamin; Folinic acid |
| Core Tip |
The core finding of this systematic review is that the medical management of autism spectrum disorder is primarily focused on controlling debilitating comorbid symptoms (e.g., aggression, gastrointestinal distress) rather than improving core social deficits, for which no medication is approved. The field is rapidly transitioning from a broad, empirical treatment approach to one of precision medicine. This shift is driven by evidence that highly targeted interventions, such as microbiota transfer therapy for children with gastrointestinal abnormalities. |
| Publish Date |
2026-05-13 08:18 |
| Citation |
Elbeltagi YM, Abd Rab El Rasool AO, Elkashlan AM, Al-Beltagi M. Medical treatment of autism spectrum disorder in children: Current evidence, controversies, and clinical challenges. World J Clin Pediatr 2026; 15(2): 117274 |
| URL |
https://www.wjgnet.com/2219-2808/full/v15/i2/117274.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v15.i2.117274 |
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