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Publication Name World Journal of Clinical Cases
Manuscript ID 117314
Country India
Received
2025-12-04 01:00
Peer-Review Started
2025-12-04 01:00
First Decision by Editorial Office Director
2025-12-18 09:24
Return for Revision
2025-12-18 09:24
Revised
2025-12-19 01:09
Publication Fee Transferred
Second Decision by Editor
2026-01-19 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-19 06:38
Articles in Press
2026-01-19 06:38
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-29 07:29
Publish the Manuscript Online
2026-02-05 06:01
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Ophthalmology
Manuscript Type Case Control Study
Article Title Retinal architecture as a determinant of brilliant blue G phototoxicity during internal limiting membrane peeling: A case series
Manuscript Source Invited Manuscript
All Author List Ramesh Venkatesh, Edwin James, Prathibha Hande, Pragati Raj, Karishma Tendulkar and Vishma Prabhu
ORCID
Author(s) ORCID Number
Ramesh Venkatesh http://orcid.org/0000-0002-4479-9390
Funding Agency and Grant Number
Corresponding Author Ramesh Venkatesh, Consultant, Department of Ophthalmology, Narayana Nethralaya, 121/C. 1st R block, West of Chord Road, Rajaji Nagar, Bangalore 560010, India. vramesh80@yahoo.com
Key Words Retinal toxicity; Brilliant blue G; Endo illumination; Outcome; Fovea
Core Tip This case series identifies retinal architecture as a key determinant of brilliant blue G (BBG)-related toxicity during internal limiting membrane peeling. Phototoxicity was more severe in macular hole (MH) cases where the exposed retinal pigment epithelium allowed direct BBG-light interaction, leading to foveal damage and poor visual recovery. Non-MH eyes, including epiretinal membrane and vitreomacular traction, retained foveal protection and demonstrated better postoperative vision. The study reinforces careful control of illumination and BBG exposure in MH surgery.
Publish Date 2026-02-05 06:01
Citation

Venkatesh R, James E, Hande P, Raj P, Tendulkar K, Prabhu V. Retinal architecture as a determinant of brilliant blue G phototoxicity during internal limiting membrane peeling: A case series. World J Clin Cases 2026; 14(4): 117314

URL https://www.wjgnet.com/2307-8960/full/v14/i4/117314.htm
DOI https://dx.doi.org/10.12998/wjcc.v14.i4.117314
Full Article (PDF) WJCC-14-117314-with-cover.pdf
STROBE Statement 117314-STROBE-statement.pdf
Manuscript File 117314_Auto_Edited_015849.docx
Answering Reviewers 117314-answering-reviewers.pdf
Audio Core Tip 117314-audio.mp3
Biostatistics Review Certificate 117314-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 117314-conflict-of-interest-statement.pdf
Copyright License Agreement 117314-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 117314-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 117314-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 117314-non-native-speakers.pdf
Peer-review Report 117314-peer-reviews.pdf
Scientific Misconduct Check 117314-scientific-misconduct-check.png
Scientific Editor Work List 117314-scientific-editor-work-list.pdf
CrossCheck Report 117314-crosscheck-report.pdf