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Articles Published Processes
6/9/2026 9:23:54 AM | Browse: 0 | Download: 0
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Received |
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2025-12-08 02:43 |
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Peer-Review Started |
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2025-12-08 02:44 |
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First Decision by Editorial Office Director |
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2026-01-08 09:30 |
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Return for Revision |
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2026-01-08 12:56 |
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Revised |
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2026-02-12 12:39 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-04-01 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-01 12:02 |
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Articles in Press |
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2026-04-01 12:02 |
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Edit the Manuscript by Language Editor |
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2026-04-06 19:40 |
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Typeset the Manuscript |
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2026-05-25 02:09 |
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Publish the Manuscript Online |
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2026-06-09 09:23 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Chemistry, Organic |
| Manuscript Type |
Opinion Review |
| Article Title |
From association to intervention: Rethinking CD24’s causal role in hepatocellular carcinogenesis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Li-Na Ren, Cong Liu, Cheng-Qiang Jin and Xiang-Hui Zhang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Cheng-Qiang Jin, Department of Laboratory Medicine, Affiliated Hospital of Jining Medical University, No. 89 Guhuai Road, Jining 272029, Shandong Province, China. jincq2008@163.com |
| Key Words |
CD24; Hepatocellular carcinoma; Programmed death-ligand 1; Immune evasion; Biomarker; Clustered regularly interspaced short palindromic repeats; Single-cell RNA sequencing; Spatial transcriptomics |
| Core Tip |
A recent study report dynamic up-regulation of CD24 during hepatocarcinogenesis, improving alpha-fetoprotein -negative hepatocellular carcinoma detection. However, this study lacks functional validation, subset resolution, and mechanistic linkage to programmed death-ligand 1. Functional genetics, single-cell, multi-omics, and spatial analyses are needed to confirm CD24’s causality and therapeutic potential. |
| Publish Date |
2026-06-09 09:23 |
| Citation |
Ren LN, Liu C, Jin CQ, Zhang XH. From association to intervention: Rethinking CD24’s causal role in hepatocellular carcinogenesis. World J Gastrointest Oncol 2026; 18(6): 117434
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| URL |
https://www.wjgnet.com/1948-5204/full/v18/i6/117434.htm |
| DOI |
https://doi.org/10.4251/wjgo.v18.i6.117434 |
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