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Articles Published Processes
6/30/2026 11:45:13 AM | Browse: 1 | Download: 16
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Received |
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2025-12-08 06:50 |
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Peer-Review Started |
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2025-12-08 06:50 |
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First Decision by Editorial Office Director |
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2026-01-15 09:37 |
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Return for Revision |
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2026-01-15 09:37 |
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Revised |
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2026-01-19 04:13 |
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Publication Fee Transferred |
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2026-01-21 05:06 |
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Second Decision by Editor |
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2026-03-05 02:53 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-05 09:33 |
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Articles in Press |
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2026-03-05 09:33 |
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Edit the Manuscript by Language Editor |
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2026-03-08 23:23 |
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Typeset the Manuscript |
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2026-05-26 06:08 |
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Publish the Manuscript Online |
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2026-06-30 11:45 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Observational Study |
| Article Title |
Effects of paroxetine on aripiprazole and individualized administration in depressed patients based on model-informed precision dosing
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ying-Wei Jin, Yue Zhang, Jie Wang, Lei Jiang, Su-Mei He, Cun Zhang and Dong-Dong Wang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science and Technology Program of Xuzhou |
No. KC25105 |
| Basic Science (Natural Science) Project of Higher Education Institutions in Jiangsu Province |
No. 25KJD310004 |
| Suzhou Applied Basic Research Science and Technology Innovation Project |
No. SYWD2024258 |
| Xuzhou Medical University Research Project on Reform of Postgraduate Education and Teaching |
No. XYJGKT202506 |
| Xuzhou Medical University Teaching Academic Research Topics |
No. 2024ZDKT02-Y03 |
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| Corresponding Author |
Dong-Dong Wang, Adjunct Professor, PhD, Principal Investigator, Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy and School of Pharmacy, Xuzhou Medical University, No. 209 Tongshan Road, Xuzhou 221004, Jiangsu Province, China. 13852029591@163.com |
| Key Words |
Drug-drug interactions; Individualized administration; Aripiprazole; Depressed patients; Model-informed precision dosing |
| Core Tip |
This study explores drug-drug interactions and optimal initial dosage of aripiprazole in depressed patients based on model-informed precision dosing. When depressed patients take paroxetine hydrochloride tablet at the same time, it will reduce the clearance rate of aripiprazole. Aripiprazole clearance rate decreases 53.3% in depressed patients taking paroxetine hydrochloride tablet. Therefore, when taking paroxetine hydrochloride tablet simultaneously, the dosage of aripiprazole should be reduced in depressed patients. |
| Publish Date |
2026-06-30 11:45 |
| Citation |
Jin YW, Zhang Y, Wang J, Jiang L, He SM, Zhang C, Wang DD. Effects of paroxetine on aripiprazole and individualized administration in depressed patients based on model-informed precision dosing. World J Psychiatry 2026; 16(7): 117458
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| URL |
https://www.wjgnet.com/2220-3206/full/v16/i7/117458.htm |
| DOI |
https://doi.org/10.5498/wjp.117458 |
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