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Articles Published Processes
4/21/2026 9:00:13 AM | Browse: 4 | Download: 17
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Received |
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2025-12-08 06:19 |
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Peer-Review Started |
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2025-12-08 10:03 |
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First Decision by Editorial Office Director |
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2025-12-24 09:42 |
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Return for Revision |
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2025-12-24 09:42 |
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Revised |
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2025-12-26 06:04 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-03-20 02:43 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-20 10:11 |
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Articles in Press |
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2026-03-20 10:11 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-03 01:58 |
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Publish the Manuscript Online |
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2026-04-21 09:00 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Systematic Reviews |
| Article Title |
MicroRNAs as diagnostic and prognostic biomarkers in chemotherapy-induced peripheral neuropathy: A systematic review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Tsampika-Vasileia Kalamara, Dimitrios A Andreikos, Konstantinos Dodos, Elisavet Georgiou, George Fotakopoulos, Nikolaos Foroglou, Dorothea Kapoukranidou and Vasiliki E Georgakopoulou |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Vasiliki E Georgakopoulou, MD, Department of Pathophysiology, Laiko General Hospital, Medical School of National and Kapodistrian University of Athens, 17 Agiou Toma Street, Athens 11527, Greece. vaso_georgakopoulou@hotmail.com |
| Key Words |
Chemotherapy-induced peripheral neuropathy; MicroRNA; Biomarker; Neurotoxicity; Liquid biopsy |
| Core Tip |
This systematic review synthesizes, for the first time, the human evidence on miRNAs as minimally invasive biomarkers of chemotherapy-induced peripheral neuropathy. Across five observational studies, 30 circulating miRNAs were profiled, with a small subset (notably miR-22-3p, hsa-miR-378f and miR-3184-5p) showing differential expression in patients with CIPN. However, inconsistent signals across cancer types and regimens, together with limited sample sizes and heterogeneous methodologies, currently preclude clinical application. The review maps the most promising candidate miRNAs and delineates key design and reporting priorities needed to move miRNA-based CIPN diagnostics and prognostics towards clinical utility. |
| Publish Date |
2026-04-21 09:00 |
| Citation |
Kalamara TV, Andreikos DA, Dodos K, Georgiou E, Fotakopoulos G, Foroglou N, Kapoukranidou D, Georgakopoulou VE. MicroRNAs as diagnostic and prognostic biomarkers in chemotherapy-induced peripheral neuropathy: A systematic review. World J Clin Oncol 2026; 17(4): 117460 |
| URL |
https://www.wjgnet.com/2218-4333/full/v17/i4/117460.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v17.i4.117460 |
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