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3/15/2026 6:19:12 AM | Browse: 5 | Download: 15
Publication Name World Journal of Experimental Medicine
Manuscript ID 117464
Country United Kingdom
Received
2025-12-24 03:23
Peer-Review Started
2025-12-24 03:24
First Decision by Editorial Office Director
2026-01-07 02:31
Return for Revision
2026-01-07 02:31
Revised
2026-01-11 21:41
Publication Fee Transferred
Second Decision by Editor
2026-02-05 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-05 08:21
Articles in Press
2026-02-05 08:21
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-27 07:08
Publish the Manuscript Online
2026-03-15 06:19
ISSN 2220-315x (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Retrospective Cohort Study
Article Title Diabetic ketoacidosis in patients with type 2 diabetes: Risk factors for mortality and adverse outcomes
Manuscript Source Invited Manuscript
All Author List Vishnu Chandrabalan, Timothy Howcroft, Mohammed Khalid Alkhalifah, Noorulanne Younis, Ebrahim Aldhafiri and Joseph M Pappachan
ORCID
Author(s) ORCID Number
Joseph M Pappachan http://orcid.org/0000-0003-0886-5255
Funding Agency and Grant Number
Corresponding Author Joseph M Pappachan, FRCP, MD, MRCP, Professor, Senior Researcher, Faculty of Science,, Manchester Metropolitan University, Manchester, Manchester M15 6BH, Greater Manchester, United Kingdom. drpappachan@yahoo.co.in
Key Words Type 2 diabetes mellitus; Diabetic ketoacidosis; Dementia; Peripheral vascular disease; Heart failure; Mortality risk
Core Tip Diabetic ketoacidosis (DKA) resulting from type 2 diabetes mellitus (T2DM) is less common. A retrospective analysis of 464 patients from a tertiary-care United Kingdom hospital with DKA and T2DM identified that mortality rates at 30 and 90 days were 13.4% and 11% respectively after the index DKA event. The survival after the DKA event was only 58.6% on long-term follow-up. Coexistent peripheral vascular disease, congestive heart failure, and lower estimated glomerular filtration rate were the important predictors of inpatient mortality. Factors associated with long-term mortality risk were dementia, and older age at presentation and continued use of older antidiabetic agents like sulfonylurea/metformin.
Publish Date 2026-03-15 06:19
Citation

Chandrabalan V, Howcroft T, Alkhalifah MK, Younis N, Aldhafiri E, Pappachan JM. Diabetic ketoacidosis in patients with type 2 diabetes: Risk factors for mortality and adverse outcomes. World J Exp Med 2026; 16(1): 117464

URL https://www.wjgnet.com/2220-315x/full/v16/i1/117464.htm
DOI https://dx.doi.org/10.5493/wjem.v16.i1.117464
Full Article (PDF) WJEM-16-117464-with-cover.pdf
STROBE Statement 117464-STROBE-statement.pdf
Manuscript File 117464_Auto_Edited_075419.docx
Answering Reviewers 117464-answering-reviewers.pdf
Audio Core Tip 117464-audio.m4a
Biostatistics Review Certificate 117464-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 117464-conflict-of-interest-statement.pdf
Copyright License Agreement 117464-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 117464-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 117464-institutional-review-board-statement.pdf
Peer-review Report 117464-peer-reviews.pdf
Scientific Misconduct Check 117464-scientific-misconduct-check.png
Scientific Editor Work List 117464-scientific-editor-work-list.pdf
CrossCheck Report 117464-crosscheck-report.pdf