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Articles Published Processes
2/11/2015 4:38:00 PM | Browse: 1145 | Download: 1614
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Received |
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2014-06-02 10:35 |
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Peer-Review Started |
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2014-06-02 21:11 |
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To Make the First Decision |
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2014-07-21 14:23 |
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Return for Revision |
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2014-07-28 16:07 |
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Revised |
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2014-08-02 14:20 |
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Second Decision |
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2014-09-19 08:51 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-09-19 09:50 |
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Articles in Press |
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2014-09-19 10:23 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-01-28 16:19 |
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Publish the Manuscript Online |
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2015-02-11 16:38 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Clinical significance and usefulness of soluble heparin binding-epidermal growth factor in gastric cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hye Won Chung, Hoon Young Kong and Jong-Baeck Lim |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Yonsei University College of Medicine for 2014 |
3-2014-0115 |
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| Corresponding Author |
Jong-Baeck Lim, MD, PhD, Department of Laboratory Medicine, Yonsei University College of Medicine, Gangnam Severance Hospital, 211 Eonjuro, Gangnam-gu, Seoul 120-752, South Korea. jlim@yuhs.ac
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| Key Words |
Biomarker; Diagnostic; Gastric cancer; Prognostic; Soluble heparin-binding EGF-like growth factor |
| Core Tip |
Early detection of gastric cancer (GC) is most important issue. Although endoscopic examination is an ideal, highly reliable technique for early detection of GC, it has limitation because of its high cost and invasiveness. Therefore, inexpensive, comfortable, reliable and less-invasive biomarkers need to be identified. Here, we reported that serum levels of soluble HB-EGF (sHB-EGF) closely correlated with advanced TNM stage and was higher in EGC than high-risk group. We also identified a remarkable diagnostic accuracy of serum sHB-EGF for GC. To our knowledge, this is the first study to validate sHB-EGF as a desirable serum biomarker for GC.
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| Publish Date |
2015-02-11 16:38 |
| Citation |
Chung HW, Kong HY, Lim JB. Clinical significance and usefulness of soluble heparin binding-epidermal growth factor in gastric cancer. World J Gastroenterol 2015; 21(7): 2080-2088 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i7/2080.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i7.2080 |
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