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Articles Published Processes
4/14/2026 8:58:01 AM | Browse: 2 | Download: 0
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Received |
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2025-12-09 00:46 |
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Peer-Review Started |
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2025-12-09 08:14 |
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First Decision by Editorial Office Director |
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2025-12-30 05:59 |
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Return for Revision |
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2025-12-30 05:59 |
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Revised |
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2026-01-10 08:08 |
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Publication Fee Transferred |
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2026-01-13 05:10 |
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Second Decision by Editor |
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2026-02-04 02:55 |
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Second Decision by Editor-in-Chief |
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2026-02-10 20:49 |
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Final Decision by Editorial Office Director |
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2026-02-11 06:36 |
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Articles in Press |
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2026-02-11 06:36 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-20 08:13 |
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Publish the Manuscript Online |
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2026-04-14 08:58 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Observational Study |
| Article Title |
Serum 25-hydroxyvitamin D and peripheral thyroid hormone sensitivity in euthyroid type 2 diabetes: Linear estimates and low-range threshold
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Chun-Yan Zhu, Zi-Ru Fang, Liang-Yan Hua, Hui Jin, Xin-Yi Xu, Xiang-Lan Liu, Yi-Ming Zhang and Zi-Chen Rao |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Zi-Chen Rao, MD, Endocrinology, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People’s Hospital, The Quzhou Affiliated Hospital of Wenzhou Medical University, No. 100 Minjiang Dadao, West District,, Quzhou 324000, Zhejiang Province, China. rzc1522@wmu.edu.cn |
| Key Words |
25-hydroxyvitamin D; Free triiodothyronine-to-free thyroxine ratio; Thyroid hormone sensitivity; Type 2 diabetes; Nonlinear association; Restricted cubic splines; Piecewise regression |
| Core Tip |
In a real-world cohort of euthyroid adults with type 2 diabetes, we examined the association between serum 25-hydroxyvitamin D and the free triiodothyronine-to-free thyroxine (FT3/FT4) ratio, a pragmatic circulating proxy of peripheral thyroid hormone sensitivity. Using multivariable models with restricted cubic splines and segmented regression, we identified a low-range threshold around 14.7 ng/mL: The positive gradient was steeper below this level and was attenuated above it. The overall pattern was broadly consistent across prespecified subgroups, with attenuation among current drinkers. These findings are associative and require longitudinal or interventional confirmation. |
| Publish Date |
2026-04-14 08:58 |
| Citation |
Zhu CY, Fang ZR, Hua LY, Jin H, Xu XY, Liu XL, Zhang YM, Rao ZC. Serum 25-hydroxyvitamin D and peripheral thyroid hormone sensitivity in euthyroid type 2 diabetes: Linear estimates and low-range threshold. World J Diabetes 2026; 17(4): 117489 |
| URL |
https://www.wjgnet.com/1948-9358/full/v17/i4/117489.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v17.i4.117489 |
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